Study of the Diaphragmatic Function by Transient Elastography (ELASTODIAPH)

NCT ID: NCT03313141

Last Updated: 2017-12-19

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 14 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2017-10-09
• Study Completion Date: 2017-10-27

Brief Summary

The study of diaphragmatic function is usually measured by the pressures and volumes generated by contraction of the diaphragm, which is often difficult (cumbersome technique, difficulty to obtain a perfect cooperation of the subjects, and difficulty to specifically analyze the diaphragm compared to other accessory respiratory muscle groups). In this study, the investigators aimed at analysing diaphragmatic function by measuring the shortening, stiffness, strain and thickening of the diaphragm by ultrasound.

Conditions

Healthy

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

Subjects

Only one arm is considered

Group Type: EXPERIMENTAL

Ultrasound

Intervention Type: DIAGNOSTIC_TEST

Volitional and non volitional respiratory tasks

Interventions

Ultrasound

Volitional and non volitional respiratory tasks

Intervention Type: DIAGNOSTIC_TEST

Other Intervention Names

Magnetic and electrical phrenic nerve stimulation

Eligibility Criteria

Inclusion Criteria

• healthy volunteer

Exclusion Criteria

• chronic respiratory, neurologic or cardiac disease
• swallowing disorders
• pregnancy

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Pitie Salpêtrière Hospital

Paris, , France

Countries

France

Other Identifiers

2015-A00949-40

Identifier Type: -

Identifier Source: org_study_id