The Effects of Attentional Filter Training on Working Memory

NCT ID: NCT03228446

Last Updated: 2019-02-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-09-26

Study Completion Date

2019-01-31

Brief Summary

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The investigators are interested in how attentional filter training/ distractor inhibition training could influence cognitive functions like working memory, executive control, problem solving, decision making and attentional control.

Detailed Description

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Two different computer based trainings were applied: an attentional filter training and a working memory training.

Conditions

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Cognitive Decline Healthy Age-related Cognitive Decline

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Young subjects

Working memory training \& attentional filter training for participants (18-30 years)

Group Type EXPERIMENTAL

filter training

Intervention Type BEHAVIORAL

one-week filter training on the computer: computerized visual change detection experiment (selective attention )

memory training

Intervention Type BEHAVIORAL

one-week storage training on the computer: computerized visual change detection experiment (memory storage)

Old subjects

Working memory training, attentional filter training and no training (control) for participants (60-80 years)

Group Type EXPERIMENTAL

filter training

Intervention Type BEHAVIORAL

one-week filter training on the computer: computerized visual change detection experiment (selective attention )

memory training

Intervention Type BEHAVIORAL

one-week storage training on the computer: computerized visual change detection experiment (memory storage)

no training (control)

Intervention Type OTHER

no training applied

Interventions

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filter training

one-week filter training on the computer: computerized visual change detection experiment (selective attention )

Intervention Type BEHAVIORAL

memory training

one-week storage training on the computer: computerized visual change detection experiment (memory storage)

Intervention Type BEHAVIORAL

no training (control)

no training applied

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* right-hander
* aged between 18-30 or 60-80years

Exclusion Criteria

* severe visual impairments (e.g. dyschromatopsia, very low vision)
* diseases or medication that might impair test performance
* Montreal Cognitive Assessment Score (MoCA) \< 26 points
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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German Research Foundation

OTHER

Sponsor Role collaborator

German Center for Neurodegenerative Diseases (DZNE)

OTHER

Sponsor Role lead

Responsible Party

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Notger Müller

Prof. Dr. med. (Head of Neuroprotection Lab at the DZNE)

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Notger Müller, Prof. Dr.

Role: PRINCIPAL_INVESTIGATOR

German Center for Neurodegenerative Diseases (DZNE)

Locations

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DZNE

Magdeburg, Saxony-Anhalt, Germany

Site Status

Countries

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Germany

References

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Schmicker M, Schwefel M, Vellage AK, Muller NG. Training of Attentional Filtering, but Not of Memory Storage, Enhances Working Memory Efficiency by Strengthening the Neuronal Gatekeeper Network. J Cogn Neurosci. 2016 Apr;28(4):636-42. doi: 10.1162/jocn_a_00922. Epub 2016 Jan 14.

Reference Type RESULT
PMID: 26765946 (View on PubMed)

Schmicker M, Muller P, Schwefel M, Muller NG. Attentional Filter Training but Not Memory Training Improves Decision-Making. Front Hum Neurosci. 2017 Mar 23;11:138. doi: 10.3389/fnhum.2017.00138. eCollection 2017.

Reference Type RESULT
PMID: 28386225 (View on PubMed)

Other Identifiers

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MD021

Identifier Type: -

Identifier Source: org_study_id

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