Effect of Non-alcoholic Fatty Liver Disease on Kidney Functions

NCT ID: NCT03172650

Last Updated: 2017-08-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-07-01

Study Completion Date

2018-09-30

Brief Summary

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Non-alcoholic fatty liver disease is the most common cause of chronic liver disease worldwide. It is defined as the accumulation of fat (\>5%) in the liver cells in the absence of excessive alcohol intake or other causes of liver disease including viral, drug-induced, or autoimmune. Non-alcoholic fatty liver disease is a hepatic manifestation of metabolic syndrome.

Detailed Description

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Conditions

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Liver Diseases

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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study group

non alcoholic fatty liver disease patients

glomerular filtration rate

Intervention Type DIAGNOSTIC_TEST

collection of blood sample 5 milliliter for calculation of glomerular filtration rate

Control group

fatty liver patients

glomerular filtration rate

Intervention Type DIAGNOSTIC_TEST

collection of blood sample 5 milliliter for calculation of glomerular filtration rate

Interventions

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glomerular filtration rate

collection of blood sample 5 milliliter for calculation of glomerular filtration rate

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* All non alcoholic fatty liver disease patients evidenced by abdominal ultrasound.
* Urine analysis whether normal or renal sedimentation.

Exclusion Criteria

1. Alcoholic fatty liver patients.
2. patients known to have diabetes mellitus.
3. patients with other causes of liver disease as viral hepatitis, drug induced,or autoimmune.
4. patients known to have kidney disease.
5. Hypertension.
6. Hyperuricemia.
7. Impaired urea and creatinine patients.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Mohamed Abbas

principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ahmed Abbas

Assiut, Cairo Governorate, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Mahmoud Ali, MBBCh

Role: CONTACT

00201144287363

Facility Contacts

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ahmed abbas, MD

Role: primary

ahmed abbas

Role: backup

Other Identifiers

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NAFLD

Identifier Type: -

Identifier Source: org_study_id

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