Analysis of Incidence and Risk Factors of Severe Cardiovascular Events in Patients With Diastolic Dysfunction

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

4347 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-08-31

Study Completion Date

2017-03-31

Brief Summary

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This retrospective cohort study was intended to analyze the incidence and risk factors of perioperative severe cardiovascular events in patients with diastolic dysfunction.

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Detailed Description

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The investigators retrospected patients underwent noncardiac surgery with pre-operative echocardiography and was diagnosed with diastolic dysfunction in 2015 in Peking University First Hospital. Patients' perioperative data were collected. Major adverse cardiovascular events(MACE), other complication incidence, and post-operative hospital stay were reviewed. propotional harzad ratio cox survival model was established. Risk and protective factors relative to MACE were analysed.

Conditions

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Diastolic Dysfunction

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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grade1&2 diastolic dysfunction

lower diastolic dysfunction exposure

No interventions assigned to this group

grade 3 diastolic dysfunction

higher diastolic dysfunction exposure

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* 18 years old or older, with echocardiographic diagnosis of left ventricular diastolic dysfunction (while ejection fraction was \> = 50%) conducted by cardiologist within 90 days before surgery.

Exclusion Criteria

* congenital heart disease, moderate to severe valvular disease (stenosis or insufficiency), atrial fibrillation / atrial flutter, pericarditis, unsatisfied cardiac ultrasound image, ejection fraction \< 50%, ASA greater than 4, or Echocardiography is missing or incomplete.

Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No