Clinical Profiles and Outcomes of Acute Aortic Dissection in the Chinese Patients

NCT ID: NCT01606943

Last Updated: 2012-05-28

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 2000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2009-01-31
• Study Completion Date: 2012-02-29

Brief Summary

Clinical profiles and outcomes of patients with acute aortic dissection have not yet been evaluated in China. The aim of this study is to establish clinical registry of acute aortic dissection in China and to analyze clinical features, managements and outcomes of Chinese patients with acute aortic dissection.

Detailed Description

In 1996, the Internation Registry of Acute Aortic Dissection(IRAD) was established to improve clinical diagnosis and treatment of acute aortic dissection. However, most patients from the IRAD are Caucasian. These data were not sufficient to reflect clinical profiles and outcomes of Chinese patients with acute aortic dissection. In China, little is known about clinical features, managements and outcomes of acute aortic dissection involving a large number of patients. The investigators established clinical multicenter registry of acute aortic dissection. Between January 2009 and February 2012, about 2000 were enrolled in the Chinese registry of acute aortic dissection(CRAD) database. The aim of this study is to analyze clinical profiles and outcomes of Chinese patients with acute aortic dissection.

Conditions

Aorta Thoracic Ascending Dissection; Dissection of Descending Aorta

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• Stanford type A dissection
• Stanford type B dissection
• Retrograde Stanford Type B dissection
• Unclassified dissection with primary tear located in the aortic dissection

Exclusion Criteria

• Aortic aneurysm
• Active infection or active vasculitides
• Myocardial infarction or Cerebral accident within 2 months
• Unwillingness to cooperate wiht study procedures or follow-up visits

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Changhai Hospital

OTHER

Sponsor Role: collaborator

Xijing Hospital

OTHER

Sponsor Role: lead

Responsible Party

Yang Li, MD

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Dihua Yi, MD

Role: STUDY_DIRECTOR

Xijing Hospital

Yang Li, MD

Role: PRINCIPAL_INVESTIGATOR

General Hospital of Beijing Military Area command of Chinese PLA

Wenxun Duan, MD

Role: PRINCIPAL_INVESTIGATOR

Xijing Hospital

Locations

Xijing Hospital

Xi'an, Shaanxi, China

Countries

China

Other Identifiers

CRAD2011

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

XJ201202

Identifier Type: -

Identifier Source: org_study_id