Clinical Characteristics, Management and Outcomes of Chinese Patients With Acute Aortic Dissection

NCT ID: NCT01552720

Last Updated: 2012-03-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-01-31

Study Completion Date

2015-12-31

Brief Summary

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Data reported by the international registry of acute aortic dissection (IRAD) in not sufficient to reflect clinical characteristics of acute aortic dissection in China. Moreover, clinical characteristics of Acute aortic dissection have not evaluated to data. The aim of this study is analyze changing trend of clinical characteristics of Chinese patients with acute aortic dissection.

Detailed Description

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Acute aortic dissection is the most common aortic emergency, with an annual incidence of 3-5 cases per 100 000 population. About 50% of these patients are dead within 48 hours, if untreated. To assess the clinical manifestation, diagnosis, management, and outcomes of patients with AAD, the International Registry of Acute Aortic Dissection (IRAD) was established in 1996, and has grown to include about 2000 patients from 26 large referral centers to date. All patients from IRAD are caucasians from developed countries wiht advanced medical care, however, the proportion of Asian is very low. Data reported by the IRAD in not sufficient to reflect clinical characteristics of Acute aortic dissection in China. Clinical characteristics of Chinese patients with acute aortic dissection have not evaluated to data. The aim of this study is to analyze clinical characteristics of Chinese patients with acute aortic dissection and clinical trend of acute aortic dissection.

Conditions

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Aortic Dissection

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of acute aortic dissection
* Type A dissection
* Type B dissection
* Retrograde type B dissection

Exclusion Criteria

* Aortic aneurysm
* Myocardial infarction
* Cerebral accident
* Active infection
* Unwillingness to cooperation with study procedures or follow-up visits
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Xijing Hospital

OTHER

Sponsor Role lead

Responsible Party

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Yang Li, MD

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Dihua Yi, PhD, MD

Role: STUDY_DIRECTOR

Xijing Hospital

Locations

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Xijing Hospital

Xi'an, Shaanxi, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yang Li, MD

Role: CONTACT

029-6787564

Facility Contacts

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Yang Li, MD

Role: primary

029-68574562

Related Links

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Other Identifiers

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CRAD201203

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

XJHEART2012

Identifier Type: -

Identifier Source: org_study_id

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