New-onset Heart Blocks After Noncardiac Surgery: a Retrospective Study of More Than 280,000 Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

281497 participants

Study Classification

OBSERVATIONAL

Study Start Date

2008-01-01

Study Completion Date

2019-08-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study aimed to investigate new-onset heart blocks after noncardiac surgery, identify risk factors, and develop a prediction model.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Study on the Protective Effect of RIPC in Patients Undergoing Cardiac Surgery.

NCT04433468

Cardiac Surgery

COMPLETED NA

Prognostic Factors of Patients Undergoing Redo Cardiac Surgery

NCT03925376

Redo Cardiac Surgery

UNKNOWN

Management Practices and the Risk of Infection Following Cardiac Surgery

NCT01089712

Cardiac Surgery Infection, Postoperative Wound Postoperative Wound Infection +2 more

COMPLETED

Atrial Fibrillation Risk After Miniinvasive Mitral Valve Repair

NCT06707506

Mitral Regurgitation Computed Tomography Atrial Fibrillation

COMPLETED

Brain-Induced Neurotrophic Factor Levels in Patients Undergoing Coronary Artery Bypass Surgery

NCT04250935

Cognitive Dysfunction

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Objective: This study aimed to investigate new-onset heart blocks after noncardiac surgery, identify risk factors, and develop a prediction model.

Methods: A retrospective cohort study included 281,497 patients aged 18 or older who underwent noncardiac surgery at a single center between Jan 2008 and Aug 2019. The main outcome was postoperative new-onset heart blocks within one year, including atrioventricular and bundle blocks. Prognostic impact was assessed using Kaplan-Meier survival curves and time-dependent Cox regression analysis. Perioperative data was used for machine learning models (logistic regression, support vector machine, random forest, decision tree). Model performance was measured using the area under the receiver operating characteristic curve (AUC).

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Heart Block Risk Factor

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Non- Heart blocks

The number of patients who did not suffered the heart blocks in the postoperative 1-year period

non interventions

Intervention Type OTHER

Heart blocks

The number of patients who suffered the heart blocks in the postoperative 1-year period

non interventions

Intervention Type OTHER

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

non interventions

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* patients above 18 yrs undergoing noncardiac surgery at the First Medical Center of the Chinese People's Liberation Army General Hospital (PLAGH) from January 1, 2008 to August 1, 2019.