Respirophasic Carotid Artery Peak Velocity Variation as a Predictor of Fluid Responsiveness in Patients With Coronary Disease

NCT ID: NCT01836081

Last Updated: 2013-04-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-12-31

Study Completion Date

2012-12-31

Brief Summary

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The aim of this study is to investigate usefulness of the respirophasic variation in carotid artery peak flow velocity measured by Doppler ultrasound, which is noninvasive and easily accessible, as a predictor of fluid responsiveness in patients with coronary artery disease.

Detailed Description

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Conditions

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Coronary Artery Occlusive Disease

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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fluid responsiveness

Group Type EXPERIMENTAL

Volume expansion

Intervention Type OTHER

Interventions

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Volume expansion

Intervention Type OTHER

Other Intervention Names

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volume expansion with 6 mL/kg of 6% hydroxylethyl starch 130/0.4

Eligibility Criteria

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Inclusion Criteria

1\. patients scheduled for elective isolated off-pump coronary artery bypass graft surgery

Exclusion Criteria

1. cardiac rhythm other than sinus
2. congestive heart failure
3. left ventricular ejection fraction \<35%
4. history of transient ischemic attack
5. pre-existing cerebrovascular disease and peripheral arterial occlusive disease
6. presence of carotid artery stenosis \>50%
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yonsei University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Yonsei University College of Medicine

Seoul, Seoul, South Korea

Site Status

Countries

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South Korea

References

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Song Y, Kwak YL, Song JW, Kim YJ, Shim JK. Respirophasic carotid artery peak velocity variation as a predictor of fluid responsiveness in mechanically ventilated patients with coronary artery disease. Br J Anaesth. 2014 Jul;113(1):61-6. doi: 10.1093/bja/aeu057. Epub 2014 Apr 9.

Reference Type DERIVED
PMID: 24722322 (View on PubMed)

Other Identifiers

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4-2011-0687

Identifier Type: -

Identifier Source: org_study_id

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