Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
60 participants
OBSERVATIONAL
2016-01-01
2022-03-01
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Diabetes and Lipid Accumulationand Heart Transplant
NCT03546062
Insulin Sensitivity, Irisin and Adipokines as Outcome Parameters in Patients Undergoing Cardiac Surgery
NCT02258698
Reversal of Obesity Cardiomyopathy
NCT01372397
Insulin Resistance : Heart Failure
NCT00486967
The Importance of Wnt-signaling After Cardiac Surgery
NCT04058496
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
COHORT
PROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
type 2 diabetes mellitus (T2DM) obese patients without left ventricle (LV) diastolic dysfunction.
abdominal plastic intervention
According to international guidelines, authors will remove the superficial abdominal fat from the patients enrolled in the study.
T2DM obese patients with first degree of left ventricle (LV) diastolic dysfunction.
abdominal plastic intervention
According to international guidelines, authors will remove the superficial abdominal fat from the patients enrolled in the study.
T2DM obese patients with second degree of left ventricle (LV) diastolic dysfunction.
abdominal plastic intervention
According to international guidelines, authors will remove the superficial abdominal fat from the patients enrolled in the study.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
abdominal plastic intervention
According to international guidelines, authors will remove the superficial abdominal fat from the patients enrolled in the study.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* T2DM obese patients under anti-diabetic full medical therapy and glycemic control.
Exclusion Criteria
* T2DM patients in poor glycemic control (HbA1c values of \>7%);
* chronic neurological disorders;
* heart failure and coronary heart disease or depression of left ventricular ejection fraction (LVEF \<55%);
* severe anemia;
* thyroid dysfunction;
* kidney failure;
* uncontrolled blood pressure (blood pressure \> 140/90 mmHg on two occasions 2 weeks apart);
* inflammatory chronic disease;
* neoplastic disease.
18 Years
75 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Campania Luigi Vanvitelli
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Celestino Sardu
Professor of Medicine
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Celestino Sardu
Naples, , Italy
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Sardu C, D'Onofrio N, Trotta MC, Balestrieri ML, Nicoletti GF, D'Amico G, Fumagalli C, Contaldi C, Pacileo G, Scisciola L, Nicoletti M, Marfella LV, Sbriscia M, Sasso FC, Signoriello G, Paolisso G, Marfella R. Could Ghrelin Expression Regulate Diastolic Cardiac Function in Type 2 Diabetic Obese Patients? Diabetes Metab Res Rev. 2025 May;41(4):e70049. doi: 10.1002/dmrr.70049.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
0408052023
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.