Postoperative Complications After Appendectomy

NCT ID: NCT03119740

Last Updated: 2023-10-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

744 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-08-01

Study Completion Date

2016-11-30

Brief Summary

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The frequency of complications after appendectomy is about 9% . The predictive value of CRP as an indicator of postoperative complications has been addressed in a small number of studies. The aim of the present retrospective analysis was to determine whether postoperative CRP levels are a reliable predictor of postoperative complications.

Detailed Description

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Background: Acute appendicitis is a common emergency in general surgery. The frequency of complications after appendectomy is about 9% \[9\]. The predictive value of CRP as an indicator of postoperative complications has been addressed in a small number of studies. The aim of the present retrospective analysis was to determine whether postoperative CRP levels are a reliable predictor of postoperative complications.

Methods: This retrospective single-center cohort study comprised 744 patients who had undergone open or laparoscopic appendectomy for clinically suspected appendicitis between 1 January 2011 and 31 December 2015 at the department of general and visceral surgery, Kepler University Hospital in Linz, Austria. Demographic data, the surgical technique, postoperative complications, histopathological findings, postoperative white blood counts, and C-reactive protein levels were evaluated.

Conditions

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Appendicitis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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open appendectomy

Patients were selected retrospectively on the basis of the documented MEL code (medical service code) of open appendectomy (AE)

No interventions assigned to this group

laparoscopic appendectomy

Patients were selected retrospectively on the basis of the documented MEL code (medical service code) of open laparoscopic appendectomy (LSK AE)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* clinically suspected appendicitis between 1 January 2011 and 31 December 2015

Exclusion Criteria

* an elective appendectomy as part of an oncological or gynecological operation tumor was found intraoperatively and required ileocecal resection or right hemicolectomy
Minimum Eligible Age

18 Years

Maximum Eligible Age

96 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kepler University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Klugsberger Bettina

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Andreas Shamiyeh, MD

Role: STUDY_DIRECTOR

Clinic for General and Visceral Surgery, Kepler University Clinic Linz

Locations

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Clinic for General and Visceral Surgery, Kepler University Clinic Linz

Linz, Upper Austria, Austria

Site Status

Countries

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Austria

References

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Barkhausen S, Wullstein C, Gross E. [Laparoscopic versus conventional appendectomy--a comparison with reference to early postoperative complications]. Zentralbl Chir. 1998;123(7):858-62. German.

Reference Type BACKGROUND
PMID: 9746989 (View on PubMed)

Izbicki JR, Knoefel WT, Wilker DK, Mandelkow HK, Muller K, Siebeck M, Schweiberer L. Accurate diagnosis of acute appendicitis: a retrospective and prospective analysis of 686 patients. Eur J Surg. 1992 Apr;158(4):227-31.

Reference Type BACKGROUND
PMID: 1352137 (View on PubMed)

Kaya B, Sana B, Eris C, Karabulut K, Bat O, Kutanis R. The diagnostic value of D-dimer, procalcitonin and CRP in acute appendicitis. Int J Med Sci. 2012;9(10):909-15. doi: 10.7150/ijms.4733. Epub 2012 Nov 13.

Reference Type BACKGROUND
PMID: 23236260 (View on PubMed)

Other Identifiers

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APPCO-017

Identifier Type: -

Identifier Source: org_study_id

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