Outcome of Elderly Patients With Appendicitis

NCT ID: NCT04791657

Last Updated: 2021-03-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-01

Study Completion Date

2020-12-31

Brief Summary

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This study aims to evaluate factors that predict 30-day complications after the surgical treatment of appendicitis in elderly patients.

Detailed Description

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Appendicitis in elderly patients is more challenging due to delayed presentation and higher comorbidities, which is associated with increased postoperative morbidity and mortality. In this study, we aim to investigate the factors that predict 30-day complications after the surgical treatment of appendicitis in elderly patients. Records of patients who underwent appendectomy for appendicitis will be extracted. The primary outcome is 30-day postoperative complications. Independent variables examined include demographics, comorbidities, preoperative laboratory values, pathological findings, and surgical features. Both univariate and multivariate regression will be performed to identify factors associated with postoperative complications.

Conditions

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Appendicitis Acute

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients without complications

Patients with uneventful recovery

Appendectomy

Intervention Type PROCEDURE

Surgical treatment for appendicitis

Patients with complications

Patients experiencing complications within 30 days postoperatively

Appendectomy

Intervention Type PROCEDURE

Surgical treatment for appendicitis

Interventions

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Appendectomy

Surgical treatment for appendicitis

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients aged 65 years and older
* Patients undergoing appendectomy for acute appendicitis (pathologically confirmed)
* Patients having complete records of clinical data and postoperative follow-up records

Exclusion Criteria

* Patients younger than 65 years
* Patients undergoing an appendectomy as part of another major operation or those with appendiceal malignancy
* Patients who are treated nonoperatively for acute appendicitis
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Gulhane Training and Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Suleyman Utku Celik

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Suleyman U Celik, MD

Role: PRINCIPAL_INVESTIGATOR

Gulhane Training and Research Hospital

Locations

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Gulhane Training and Research Hospital

Ankara, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Angeramo CA, Dreifuss NH, Giacone J, Schlottmann F. Outcomes of Acute Appendicitis in Elderly Patients: a Single Center Analysis of 2000 Laparoscopic Appendectomies. J Gastrointest Surg. 2020 Dec;24(12):2859-2861. doi: 10.1007/s11605-020-04726-z. Epub 2020 Aug 31. No abstract available.

Reference Type BACKGROUND
PMID: 32865733 (View on PubMed)

Yang J, Yu K, Li W, Si X, Zhang J, Wu W, Cao Y. Laparoscopic Appendectomy for Complicated Acute Appendicitis in the Elderly: A Single-center Experience. Surg Laparosc Endosc Percutan Tech. 2017 Oct;27(5):366-368. doi: 10.1097/SLE.0000000000000447.

Reference Type BACKGROUND
PMID: 28708770 (View on PubMed)

Hui TT, Major KM, Avital I, Hiatt JR, Margulies DR. Outcome of elderly patients with appendicitis: effect of computed tomography and laparoscopy. Arch Surg. 2002 Sep;137(9):995-8; discussion 999-1000. doi: 10.1001/archsurg.137.9.995.

Reference Type BACKGROUND
PMID: 12215147 (View on PubMed)

Pokharel N, Sapkota P, Kc B, Rimal S, Thapa S, Shakya R. Acute appendicitis in elderly patients: a challenge for surgeons. Nepal Med Coll J. 2011 Dec;13(4):285-8.

Reference Type BACKGROUND
PMID: 23016482 (View on PubMed)

Other Identifiers

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Gulhane2021-51

Identifier Type: -

Identifier Source: org_study_id

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