Antimicrobial Pastes and Clinical Cases of Apexogenesis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-11-25

Study Completion Date

2016-10-08

Brief Summary

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The aim of this study was to perform a clinical and microbiological evaluation of teeth with incomplete apexogenesis and traumatic necrosis that were treated with a revascularization technique, evaluating the microbial reduction after the use a double antibiotic paste. Furthermore, the investigation also aims to identify the presence of Enterococcus faecalis and Porphyromomas gingivalis within the root canal system.

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Detailed Description

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This investigation is a longitudinal prospective interventional study of a series of cases. Patients who sought treatment at the Faculty of Dentistry from June 2011 to September 2015 were selected. They should have one permanent tooth with traumatic necrosis.

Conditions

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Apexification Root Canal Therapy Dental Trauma

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

This investigation is a longitudinal prospective interventional study of a series of cases

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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permanent teeth apexification

They should have one permanent tooth with traumatic necrosis, which in turns should show color alteration, fistulae, periapical lesion, and/or internal or external root resorption, pain, or absence of pulp response to sensitivity tests at a clinical examination to be considered necrotic. Male and female patients who had not undergone antibiotic therapy 3 months before the treatment were included and clinical and radiographic examinations confirmed pulp necrosis. This study analyzed the clinical and microbiological results of the endodontic treatment performed on permanent teeth with necrosis caused by traumatic injury and treated using revascularization technique, double antibiotic paste, intra-canal medication, and an MTA cervical plug.

Group Type EXPERIMENTAL

Apexification

Intervention Type PROCEDURE

Apexification forms a calcified barrier in teeth with open apexes and pulp necrosis. It is used to treat immature teeth, but it does not promote the continuity of root formation.

Interventions

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Apexification

Apexification forms a calcified barrier in teeth with open apexes and pulp necrosis. It is used to treat immature teeth, but it does not promote the continuity of root formation.

Intervention Type PROCEDURE

Other Intervention Names

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Pulp Revascularization

Eligibility Criteria

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Inclusion Criteria

* They should have one permanent tooth with traumatic necrosis, which in turns should show color alteration, fistulae, periapical lesion, and/or internal or external root resorption, pain, or absence of pulp response to sensitivity tests at a clinical examination to be considered necrotic. Male and female patients who had not undergone antibiotic therapy 3 months before the treatment were included and clinical and radiographic examinations confirmed pulp necrosis.

Exclusion Criteria

* Patients who did use antibiotics
* Patients who did loss of temporary coronary sealing between treatment sessions
* Patients who give up the research

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes