Correlation Between Pi Max and Diaphragm Maximum Inspiratory Excursion Detected With Ultrasound During Weaning

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2022-04-04

Study Completion Date

2024-12-31

Brief Summary

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This study evaluates the correlation between maximum inspiratory pressure (Pi max) and the diaphragm maximum inspiratory excursion measured with ultrasound during the weaning from invasive mechanical ventilation.

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Detailed Description

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Conditions

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Weaning Diaphragm Ultrasound Maximum Inspiratory Pressure

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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case group

diaphragm ultrasounds during weaning and Pimax measures

diaphragm ultrasound

Intervention Type DIAGNOSTIC_TEST

For each patient intubated and ventilated in our ICU we will performed diaphragm ultrasound during the weaning process.

We will performed the measurement of diaphragmatic maximum excursion during a maximal inspiration using an abdominal standard preset with M-mode, with the so called anatomical M-mode.

We will put the probe in the right subcostal window to use the hepatic window to assess the movement of the diaphragm. We will performed the measure of the diaphragm excursion with patient in semi-recumbent position and through a transhepatic transverse oblique scan while the patient is on mechanical ventilation and undergo a Pimax maneuver, that consists in a temporary occlusion of the airway with an expiratory pause.

We will performed the measure three times, and we will take into account the best one made by the patient.

Interventions

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diaphragm ultrasound

For each patient intubated and ventilated in our ICU we will performed diaphragm ultrasound during the weaning process.

We will performed the measurement of diaphragmatic maximum excursion during a maximal inspiration using an abdominal standard preset with M-mode, with the so called anatomical M-mode.

We will put the probe in the right subcostal window to use the hepatic window to assess the movement of the diaphragm. We will performed the measure of the diaphragm excursion with patient in semi-recumbent position and through a transhepatic transverse oblique scan while the patient is on mechanical ventilation and undergo a Pimax maneuver, that consists in a temporary occlusion of the airway with an expiratory pause.

We will performed the measure three times, and we will take into account the best one made by the patient.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age \> 18 years.
* Invasive Mechanical Ventilation \> 24 hours.
* Readiness for weaning (following clinician decision made according to recent guidelines).