Bed Rest, Inactivity and Early Responses

NCT ID: NCT02981927

Last Updated: 2018-05-25

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 10 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2015-01-31
• Study Completion Date: 2016-12-02

Brief Summary

To evaluate the early metabolic responses (whole body and within muscle tissue) to a single day of whole body physical inactivity (i.e. bed-rest), and evaluate the contribution of inactivity per se vs alterations in diet

Conditions

Metabolic Responses to Inactivity

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

Control

24 h habitual physical activity fed in energy balance

Group Type: NO_INTERVENTION

No interventions assigned to this group

Bed rest matched diet

24 hour period of whole body bed-rest with a matched diet

Group Type: EXPERIMENTAL

Physical inactivity

Intervention Type: OTHER

Bed rest balanced diet

24 hour period of whole body bed-rest fed in energy balance

Group Type: EXPERIMENTAL

Physical inactivity

Intervention Type: OTHER

Interventions

Physical inactivity

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Healthy and aged 18-40 y
• BMI between 18 and 30

Exclusion Criteria

• On medication
• Family history of metabolic disease
• Diagnosed with any metabolic or cardiovascular conditions
• BMI < 18 or > 30

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 40 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: Yes

Sponsors

University of Exeter

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Sport & Health Sciences

Exeter, Devon, United Kingdom

Countries

United Kingdom

Other Identifiers

157758/02

Identifier Type: -

Identifier Source: org_study_id