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The Effect of Frequency and Duration of Breaks in Sitting Time on Metabolic Cardiovascular Risk Factors

NCT ID: NCT02951624

Last Updated: 2018-12-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-11-30

Study Completion Date

2018-07-15

Brief Summary

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The primary aim of this study is to investigate the acute effect of the frequency and duration of breaks in sitting time on the metabolic risk factor profile.

Detailed Description

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Fifteen (n=15) sedentary adult overweight males will be included in the study. All participants will undergo the four interventions in a randomized cross-over design. Wash out between intervention will be minimum four days.

Control (CON): Participants will be sedentary. Sedentary time will be spent sitting in a chair, restricted to sedentary behaviors (working on a computer, reading, watching TV, etc.), with a target MET below 1.5 (i.e. 1.5 times REE). Participants will only be allowed to stand or walk to go to the toilet.

Breaker: Participants will be breaking up prolonged sitting with 2 min intervals of low intensity walking.

Intermediate: Participants will be breaking up prolonged sitting with 6 min intervals of low intensity walking

Prolonger: Participants will be breaking up prolonged sitting with 12 min intervals of low intensity walking

All interventions will be matched for total physical activity as well as sitting. Thus, we aim for the active interventions to be iso-caloric.

Conditions

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Sedentary Lifestyle Overweight and Obesity Metabolic Disease

Keywords

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Exercise Breaking prolonged sitting physical activity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Control

Participants will spend 8 hours sedentary. Sedentary time will be spent sitting in a chair, restricted to sedentary behaviors (working on a computer, reading, watching TV, etc.) Participants will only be allowed to stand or walk to go to the toilet.

Group Type EXPERIMENTAL

Control

Intervention Type BEHAVIORAL

Control intervention

Breaker

Participants will spend a total of 7 hours and 12 min sedentary and a total of 48 min breaking sitting time with LPA. Sedentary time will be done in bouts of 18 min with 2 min of light walking.

Group Type EXPERIMENTAL

Breaker

Intervention Type BEHAVIORAL

Short breaks of physical activity

Intermediate

Total duration of sedentary time and LPA time will be the same as in Breaker. Sedentary time will be done in bouts of 54 min with 6 min of LPA between each bout.

Group Type EXPERIMENTAL

Intermediate

Intervention Type BEHAVIORAL

Intermediate breaks of physical activity

Prolonger

Total duration of sedentary time and LPA time will be the same as in Breaker. Sedentary time will be done in bouts of 108 min with 12 min of LPA between each bout.

Group Type EXPERIMENTAL

Prolonger

Intervention Type BEHAVIORAL

longer breaks of physical activity

Interventions

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Control

Control intervention

Intervention Type BEHAVIORAL

Breaker

Short breaks of physical activity

Intervention Type BEHAVIORAL

Prolonger

longer breaks of physical activity

Intervention Type BEHAVIORAL

Intermediate

Intermediate breaks of physical activity

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Males, age 20-50 years, waist-to-height ratio ≥ 0.5 and/or waist circumference ≥ 102 cm.

Exclusion Criteria

* Clinically diagnosed diabetes, uncontrolled hypertension, use of glucose- and/or lipid-lowering medication, smoking, evidence of thyroid, liver, lung, heart or kidney disease, non-sedentary occupation, and VO2max levels above the considered average fitness according to age (Shvartz \& Reibold 1990), contraindications to increased levels of physical activity.
Minimum Eligible Age

20 Years

Maximum Eligible Age

50 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Rigshospitalet, Denmark

OTHER

Sponsor Role lead

Responsible Party

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Mathias Ried-Larsen

Group leader

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mathias Ried, PhD

Role: PRINCIPAL_INVESTIGATOR

Group leader

Locations

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Center for Physical Activity Research, Copenhagen University Hospital

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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53476

Identifier Type: -

Identifier Source: org_study_id