Conventional Bite Wing Radiography Versus Stationary Intraoral Tomosynthesis, a Comparison Study

NCT ID: NCT02873585

Last Updated: 2020-09-02

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-04-19

Study Completion Date

2019-09-30

Brief Summary

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A comparison of caries detection rates between conventional intraoral bitewing radiography and a stationary intraoral digital tomosynthesis (s-IOT) using a carbon nanotube X-ray source array. The secondary objective is to assess participants experience with the s-IOT device.

Detailed Description

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The primary purpose of this study is to compare caries detection rates between conventional intraoral bitewing radiography and a stationary intraoral digital tomosynthesis (s-IOT) using a carbon nanotube X-ray source array. Patient experience with the s-IOT device will be assess using a short questionnaire.

Fifty adult patients who have been referred to the Section of Oral and Maxillofacial Radiology (OMR) at the University of North Carolina (UNC) School of Dentistry (SOD) for horizontal bitewing (BW) radiographs or a Full Mouth Series (FMX) with horizontal bitewing radiographs will be recruited for the study.

Participants will receive an experimental s-IOT bitewing radiograph on each side of their mouth and a visual exam to look for caries. Experienced observers will assess the presence or absence of caries using the two imaging modalities. The results of their analysis will be evaluated to determine statistical difference. Participants completed questionnaires will be tabulated and the data will be analyzed using descriptive statistics.

Conditions

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Dental Caries

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Stationary intraoral tomosynthesis

Stationary intraoral tomosynthesis after standard conventional bitewing radiography

Group Type EXPERIMENTAL

Stationary intraoral tomosynthesis

Intervention Type DEVICE

Bitewing radiographs using a stationary intraoral tomosynthesis unit

Standard conventional bitewing radiography

Intervention Type DEVICE

Bitewing radiographs using a stationary intraoral tomosynthesis unit will be performed after standard bitewing radiography

Interventions

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Stationary intraoral tomosynthesis

Bitewing radiographs using a stationary intraoral tomosynthesis unit

Intervention Type DEVICE

Standard conventional bitewing radiography

Bitewing radiographs using a stationary intraoral tomosynthesis unit will be performed after standard bitewing radiography

Intervention Type DEVICE

Other Intervention Names

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Dental tomosynthesis

Eligibility Criteria

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Inclusion Criteria

* 18 years and older
* Scheduled for horizontal BW or Full (FMX) with horizontal BWs
* Patients who have in the right and left maxilla and mandible at least a canine and two posterior teeth that are in contact
* At least one proximal caries lesion in a surface of a posterior tooth (premolar or molar) that is in contact with another tooth. Lesion depth can be incipient (outer half enamel), moderate (inner half enamel) or advanced (outer half dentin) as determined by conventional BW radiography.
* At least one non-carious proximal surface of a posterior tooth (premolar or molar) that is in contact with another tooth.
* Patients should be able to provide informed consent

Exclusion Criteria

* Institutionalized subject (prisoners, nursing home, etc.) (identified by medical record)
* Critically ill or mentally unstable patients (identified by medical record)
* Patients with no radiographic caries of the posterior teeth as determined by conventional BW radiographs
* Patients with only severe caries lesions as determined by conventional BW radiographs
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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XinVivo, Inc.

INDUSTRY

Sponsor Role collaborator

North Carolina Translational and Clinical Sciences Institute

OTHER

Sponsor Role collaborator

University of North Carolina, Chapel Hill

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Angela Broome, DDS

Role: PRINCIPAL_INVESTIGATOR

UNC-School of Dentistry

Locations

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UNC School of Dentistry

Chapel Hill, North Carolina, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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16-0194

Identifier Type: -

Identifier Source: org_study_id

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