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Clinical Assessment of Caries and Dental Plaque Based on Auto-fluorescence Imaging System

NCT ID: NCT03038412

Last Updated: 2017-01-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-05-31

Study Completion Date

2017-09-30

Brief Summary

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The purpose of this study was to evaluate the applicability of auto-fluorescence imaging system to detect and quantify caries and dental plaque. Participants were advised to rinse their mouth with distilled water to exclude any chance of fluorescence from food debris. A well trained physicist majored in optical spectroscopy captured auto-fluorescence images of buccal aspects of two maxillary central incisors and occlusal aspects of four first molars from each patient in a dark room. Then they chewed a disclosing agent to assess the Quigley Hein plaque index modified by Turesky of each tooth. Furthermore, participants were also required to brush their teeth for 3min, then International Caries Detection and Assessment System（ICDAS）codes of relevant teeth to evaluate degrees of caries were recorded by an experienced dentist using a mouth mirror and explorer. The Spearman rank correlation coefficient between colorimetric parameters of fluorescence image and the plaque index and ICDAS code were calculated to evaluate the sensitivity and specificity of auto-fluorescence imaging system.

Detailed Description

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Conditions

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Dental Caries (Diagnosis) Dental Plaque Optical Imaging

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

Subjects were required to:

* 1\. have two maxillary central incisors and four first molars in mouth;
* 2\. have caries in their mouth or have a high risk to get caries and need to be treated by dentists ;
* 3\. sign informed consent form.

Exclusion Criteria

* 1.two incisors and four first molars of participants ever received endodontics treatment;
* 2\. history of antibiotics, mouthwashes, or any periodontal treatment during the last 3 months;
* 3.with calculus and cementum exposed in tooth cervical;
* 4\. active systemic disease;
* 5\. physical or mental disability;
* 6\. pregnant or lactating.
Minimum Eligible Age

18 Years

Maximum Eligible Age

54 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hui Chen

OTHER

Sponsor Role lead

Responsible Party

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Hui Chen

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Hui Chen

Role: STUDY_CHAIR

Affiliated Hospital of Stomatology, College of Medicine, Zhejiang University

Other Identifiers

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DHZhejiangU1

Identifier Type: -

Identifier Source: org_study_id