Study Results
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Basic Information
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RECRUITING
NA
40 participants
INTERVENTIONAL
2016-06-30
2025-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Control
Local anesthesia, rubber dam isolation, remove caries incompletely, microbiological sample with otoscope curette, dentin washed with sodium 0.9% saline, sampling again. Indirect pulp treatment with calcium hydroxide(CH). Restoration with resin(Z350,3M). Follow up at 6, 12 and 24 months.
Local anesthesia and rubber dam isolation
Local anesthesia was performed. Tooth was isolated using a rubber dam isolation in order to collect the dentin samples.
Incomplete caries removal and microbiological samples collection
Partial carious tissue was removed with conventional dentinal curette and collection of dentin with a spoon (1#) was performed.
Dentin washed with sodium 0.9% saline
The remaining dentin was dipped in sodium 0.9% saline for 2min.
Microbiological samples collection and Indirect pulp treatment
A new dentin collection was performed after this treatment at another site of the cavity. Then teeth were conventionally restored using the following materials: calcium hydroxide lining material and resin (Z350,3M).
PDT+CH
Local anesthesia, rubber dam isolation, remove caries incompletely, microbiological sample with otoscope curette, disinfect the remaining dentin with antimicrobial photodynamic therapy (DENFOTEX PADplus), sampling again. Indirect pulp treatment with calcium hydroxide(CH). Restoration with resin(Z350,3M). Follow up at 6, 12 and 24 months.
Local anesthesia and rubber dam isolation
Local anesthesia was performed. Tooth was isolated using a rubber dam isolation in order to collect the dentin samples.
Incomplete caries removal and microbiological samples collection
Partial carious tissue was removed with conventional dentinal curette and collection of dentin with a spoon (1#) was performed.
Antimicrobial Photodynamic Therapy
The remaining dentin was disinfected with aPDT for 2 min.
Microbiological samples collection and Indirect pulp treatment
A new dentin collection was performed after this treatment at another site of the cavity. Then teeth were conventionally restored using the following materials: calcium hydroxide lining material and resin (Z350,3M).
Interventions
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Local anesthesia and rubber dam isolation
Local anesthesia was performed. Tooth was isolated using a rubber dam isolation in order to collect the dentin samples.
Incomplete caries removal and microbiological samples collection
Partial carious tissue was removed with conventional dentinal curette and collection of dentin with a spoon (1#) was performed.
Dentin washed with sodium 0.9% saline
The remaining dentin was dipped in sodium 0.9% saline for 2min.
Antimicrobial Photodynamic Therapy
The remaining dentin was disinfected with aPDT for 2 min.
Microbiological samples collection and Indirect pulp treatment
A new dentin collection was performed after this treatment at another site of the cavity. Then teeth were conventionally restored using the following materials: calcium hydroxide lining material and resin (Z350,3M).
Eligibility Criteria
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Inclusion Criteria
* Permanent tooth with deep carious lesion (2/3 of dentin) without pain symptomatology and compatible with reversible pulpits
Exclusion Criteria
* Allergic to photosensitizer
* Unlikely to be able to comply with the study procedures
ALL
No
Sponsors
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Fujian Medical University
OTHER
Responsible Party
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Xiaojing Huang
DDS, PhD, Professor，Vice Dean，School and Hospital of Stomatology Fujian Medical University
Principal Investigators
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Xiaojing Huang, PhD
Role: STUDY_CHAIR
School and Hospital of stomatology, Fujian Medical University
Locations
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School and Hospital of Stomatology, Fujian Medical University
Fuzhou, Fujian, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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PDT20160602
Identifier Type: -
Identifier Source: org_study_id
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