Two Preventive Measures on Caries Progression in Mixed Dentition Patients.

NCT ID: NCT06119126

Last Updated: 2023-11-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

23 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-06-01

Study Completion Date

2023-10-01

Brief Summary

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Primary Objective:

Assessing the clinical effect of SDF and Laser on the prevention of initial caries progression with and without pits and fissure sealants in both permanent and primary molars.

Secondary Objective:

Effect of SDF and Laser Application on the subsequently applied pits and fissure sealants.

Detailed Description

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Primary Objective:

Assessing the clinical effect of SDF and Laser on the prevention of initial caries progression with and without pits and fissure sealants in both permanent and primary molars.

Scoring caried out by ICDAS Scoring criteria over a 1 year follow up period

Secondary Objective:

Effect of SDF and Laser Application on the subsequently applied pits and fissure sealants.

Measured by Simonson's criteria over 1 year follow up period.

Conditions

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Dentist's Role

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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Group A

Diode laser application only

Group Type EXPERIMENTAL

Diode Laser

Intervention Type DEVICE

Irradiating Enamel by Diode laser

Group B

SDF application only

Group Type EXPERIMENTAL

SDF1

Intervention Type DRUG

Topical SDF application

Group C

Diode laser application followed by pits and fissure sealant.

Group Type EXPERIMENTAL

Diode Laser

Intervention Type DEVICE

Irradiating Enamel by Diode laser

Pit Fissure Sealant

Intervention Type DRUG

Sealing occlusal pits and fissures

Group D

SDF application followed by pits and fissure sealant.

Group Type EXPERIMENTAL

SDF1

Intervention Type DRUG

Topical SDF application

Pit Fissure Sealant

Intervention Type DRUG

Sealing occlusal pits and fissures

Interventions

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SDF1

Topical SDF application

Intervention Type DRUG

Diode Laser

Irradiating Enamel by Diode laser

Intervention Type DEVICE

Pit Fissure Sealant

Sealing occlusal pits and fissures

Intervention Type DRUG

Other Intervention Names

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silver diamine fluoride Class 4 dental laser PFS

Eligibility Criteria

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Inclusion Criteria

.Children aged 6-9 years old.

.Patients categorized as moderate to high caries risk (deft index \>1) showing more than 1 new carious lesions or restorations in the last 36 months according to "ADA Caries Risk Assessment Form (Age \>6)" .A split mouth study design was followed where all four second molars were selected for intervention in the primary molar group, while all first molars were selected for intervention in the permanent molar group.

.The four molars selected in each patient (primary / permanent) should be fully erupted with no gingival overhangs /operculum and with no history of previous restorations or prior sealants.

.According to International Caries Detection and Assessment System ICDAS grading, molars with (0, 1, 2) scores only were included.

Exclusion Criteria

.Uncooperative or mentally challenged patients, with bad oral hygiene or rampant caries.

.Patients providing history of bruxism or clenching affecting the posterior occlusion were excluded.

.Children with known allergies or sensitivities to resins or silver products. .Molars that showed well-coalesced, self-cleansing pits \& fissures or shallow grooves and severe forms of hypoplasia / fluorosis were excluded.

.Patients \& parents with high esthetic demands and concerns. .Unmotivated patients, or parents who refused to sign the consent form.
Minimum Eligible Age

6 Years

Maximum Eligible Age

9 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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British University In Egypt

OTHER

Sponsor Role lead

Responsible Party

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Islam el guindy

Assistant Lecturer in Pediatric Dentistry

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Noha Kabil, Professor

Role: STUDY_DIRECTOR

Head of Department

Basma Gamal, Lecturer

Role: STUDY_DIRECTOR

Faculty Council Member

Locations

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Faculty of Dentistry British University

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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PED 20-3D

Identifier Type: -

Identifier Source: org_study_id

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