Neurophysiological Evaluation of Training Effect on Cancer-Related Weakness
NCT ID: NCT02844504
Last Updated: 2020-10-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
23 participants
INTERVENTIONAL
2016-05-31
2020-09-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Low Intensity Exercise Training 1
Cancer survivors will receive low intensity handgrip exercise training.
Low Intensity Exercise Training 1
Subjects will perform handgrip exercise training at low intensity (20% maximal force) 5 times a week for 6 weeks (more details not provided to keep study blinded)
Low Intensity Exercise Training 2
Cancer survivors will receive low intensity handgrip exercise training different than other arm.
Low Intensity Exercise Training 2
Subjects will perform a different handgrip exercise training at low intensity (20% maximal force) 5 times a week for 6 weeks (more details not provided to keep study blinded)
Control
This group will receive no training.
No interventions assigned to this group
Interventions
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Low Intensity Exercise Training 1
Subjects will perform handgrip exercise training at low intensity (20% maximal force) 5 times a week for 6 weeks (more details not provided to keep study blinded)
Low Intensity Exercise Training 2
Subjects will perform a different handgrip exercise training at low intensity (20% maximal force) 5 times a week for 6 weeks (more details not provided to keep study blinded)
Eligibility Criteria
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Inclusion Criteria
* Right handed, as determined by the Edinburgh Inventory (Oldfield, 1971)
* Proficient in English
* Must be available for the familiarization, and testing sessions
Exclusion Criteria
* Significant cognitive impairments as defined by a score \<28 in the Folstein Mini-Mental Screening Examination (MMSE, Folstein et al .1975).
* Participated in any type of motor imagery or strength training program in the last 5 years, or plan to start any motor imagery or physical strength training program for the 3 months duration of the study
* Neurological, psychiatric, musculoskeletal or other types of disorder that may affect participants sensorimotor function and cognitive abilities
* Current medication believed to affect cognitive/psychomotor function (i.e., opioid, analgesics, anxiolytics or antidepressants)
* History of alcohol, smoking, and drug abuse
* Any contraindication for MRI
40 Years
75 Years
FEMALE
Yes
Sponsors
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National Cancer Institute (NCI)
NIH
Kessler Institute for Rehabilitation
INDUSTRY
Kessler Foundation
OTHER
Responsible Party
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Principal Investigators
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Guang Yue, PhD
Role: PRINCIPAL_INVESTIGATOR
Kessler Foundation
Locations
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Kessler Foundation
West Orange, New Jersey, United States
Kessler Institute for Rehabilitation
West Orange, New Jersey, United States
Countries
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Other Identifiers
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R-849-14
Identifier Type: -
Identifier Source: org_study_id
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