Comparison of the Hemodynamic Safety of Two Common Alveolar Recruitment Manoeuvres With Regard to Cardiac Output in a Surgical Intensive Care Unit
NCT ID: NCT02805036
Last Updated: 2017-02-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
30 participants
OBSERVATIONAL
2015-11-30
2016-11-30
Brief Summary
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In contrast, there is no consensus on the type of recruitment manoeuvre, which varies from one centre to another and from one study to another.
The investigators intend to compare two currently used AR techniques with regard to their ventilatory efficacy and hemodynamic safety:
* An end-tidal plateau at 30 cmH20 for 30 seconds.
* An end-tidal plateau at 10 cmH20 above the patient's plateau pressure for 30 seconds, without exceeding 30 cmH20.
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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30 cmH20 for 30 seconds
plateau pressure is hold on at 30 cmH20 pour 30 seconds. The cardiac output and the lung aeration is assessed by ultrasound measures at 3 times: before, at the end of the recruitment and 30 minutes later.
echocardiography - arterial oximetry
echocardiography
• Prospective, simultaneous recording of the cardiac output (measured non-invasively via transthoracic echocardiography) and a number of parameters commonly monitored in the surgical intensive care unit (CVP, SBP/DBP/MBP).
Arterial oximetry
measured by co-oximetry of a blood sample taken via the arterial catheter implemented for critical care
10 cmH20 above
plateau pressure is hold on at 10 cmH20 above. The cardiac output and the lung aeration is assessed by ultrasound measures at 3 times: before, at the end of the recruitment and 30 minutes later.
echocardiography - arterial oximetry
echocardiography
• Prospective, simultaneous recording of the cardiac output (measured non-invasively via transthoracic echocardiography) and a number of parameters commonly monitored in the surgical intensive care unit (CVP, SBP/DBP/MBP).
Arterial oximetry
measured by co-oximetry of a blood sample taken via the arterial catheter implemented for critical care
Interventions
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echocardiography
• Prospective, simultaneous recording of the cardiac output (measured non-invasively via transthoracic echocardiography) and a number of parameters commonly monitored in the surgical intensive care unit (CVP, SBP/DBP/MBP).
Arterial oximetry
measured by co-oximetry of a blood sample taken via the arterial catheter implemented for critical care
Eligibility Criteria
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Inclusion Criteria
* Good echogenicity
* Social security coverage
Exclusion Criteria
* Cardiac arrhythmia
* Poor echogenicity
* Legal guardianship or incarceration
* Systolic blood pressure ≤90 mmHg
* Respiratory distress
* Patients admitted on an emergency basis (first 24 hours), i.e. not for elective surgery
18 Years
ALL
No
Sponsors
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Centre Hospitalier Universitaire, Amiens
OTHER
Responsible Party
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Principal Investigators
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Emmanuel LORNE, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
CHU Amiens
Locations
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CHU Amiens
Amiens, , France
Countries
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Other Identifiers
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PI2015_843_0002
Identifier Type: -
Identifier Source: org_study_id
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