The Causative Insects in Severe Insect Sting Allergy

NCT ID: NCT02764242

Last Updated: 2016-05-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-02-28

Study Completion Date

2016-04-30

Brief Summary

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Study the causative insect by skin prick test and sIgE to wasp, bee and fire ants are important but false positive by crossreactivity can occur. sIgE to recombinant venom allergen is proposed to help in finding the causative insect.

Detailed Description

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Insect sting allergy from insects in Hymenoptera is not uncommon. The reaction maybe very severe and life threatening. To find the cause of insect sting allergy is important in prevention and specific treatment such as immunotherapy. The skin prick test and sIgE of these insects may have cross reactions so it is difficult to be interpreted.

The usage of sIgE recombinant venom allergen can benefit in separate cross reaction and dual allergy reaction.

Conditions

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Insect Sting Allergy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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insect sting allergy

Skin prick tests to local and imported insect sting allergen with different concentration are performed.

sIgE Measurement (to insect and the recombinant venom)

Group Type OTHER

Skin prick test

Intervention Type OTHER

Skin prick tests to local and imported insect sting allergen with different concentration are performed.

sIgE measurement

Intervention Type OTHER

sIgE levels to stinging insect allergen and their recombinant venom allergen are measured

Interventions

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Skin prick test

Skin prick tests to local and imported insect sting allergen with different concentration are performed.

Intervention Type OTHER

sIgE measurement

sIgE levels to stinging insect allergen and their recombinant venom allergen are measured

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Cases with severe insect sting allergy reactions

Exclusion Criteria

* Without other severe systemic diseases
* Not pregnant or lactation
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mahidol University

OTHER

Sponsor Role lead

Responsible Party

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Nualanong Visitsunthorn

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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Si063/2557

Identifier Type: -

Identifier Source: org_study_id

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