Performance of CAST (Cellular Antigen Stimulation Test) in Patients With Wasp Venom Allergy: Evaluation of Neutralizing IgG Subclasses

NCT ID: NCT00794287

Last Updated: 2015-06-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2009-01-31

Brief Summary

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To determine which subclass of IgG in the serum of patients undergoing SIT against wasp venom is able to neutralize the allergen, and therefore to prevent a positive CAST

Detailed Description

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Conditions

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Wasp Venom Allergic Patients

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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1

Hymenoptera allergic patients before allergen specific immunotherapy

Taking blood samples

Intervention Type OTHER

No intervention is done. Only blood samples are taken.

2

Hymenoptera allergic patients after allergen specific immunotherapy

Taking blood samples

Intervention Type OTHER

No intervention is done. Only blood samples are taken.

Interventions

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Taking blood samples

No intervention is done. Only blood samples are taken.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* male and female patient with allergy to wasp venom grade III and IV according to H.L. Müller
* 18-75 years
* planned SIT against wasp venom or finished 5 years SIT against wsp venom (10/10)

Exclusion Criteria

* oral corticosteroids
* chromogycin
* ketotifen
* immunosuppressive drugs within the last 2 years
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Zurich

OTHER

Sponsor Role lead

Responsible Party

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University of Zurich

Principal Investigators

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01 Studienregister MasterAdmins

Role: STUDY_DIRECTOR

UniversitaetsSpital Zuerich

Locations

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Zurich, , Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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ZU-AgNT-004

Identifier Type: -

Identifier Source: org_study_id

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