Comparison of Skin Prick Testing and Intradermal Skin Test Result of Local and Imported Insect Allergen Extracts

NCT ID: NCT03645291

Last Updated: 2019-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

27 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-06-20

Study Completion Date

2019-07-30

Brief Summary

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Comparison the results of skin prick testing and Intradermal skin test result of local and imported insect allergen extracts in patients with serious insect sting allergy reactions

Detailed Description

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The patients with serious insect sting allergy reactions were evaluated and skin prick test and intradermal test with local and imported insect allergen extracts were performed. Specific IgE for insects was also performed. The results of skin prick testing and Intradermal skin test of local and imported insect allergen extracts were compared. The results also compared with specific IgE to insects

Conditions

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Allergy to Arthropod Sting

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Comparison of skin prick testing and Intradermal skin test result of local and imported insect allergen extracts in patients with severe insect sting allergy
Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors
None of the patients and participants know the type of insect allergen extracts used in skin prick and intradermal test

Study Groups

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Skin test with local extract

Skin prick test and intradermal test with local stinging insect allergen extracts that develop in Immunological division of Siriraj hospital, mahidol University

Group Type ACTIVE_COMPARATOR

Local insect allergen extracts skin test

Intervention Type DIAGNOSTIC_TEST

Every patient received both local and commercial insect allergen extracts but in blinded methods

Skin test with commercial extract

Skin prick test and intradermal test with commercial stinging insect allergen extracts that order from ALK company

Group Type SHAM_COMPARATOR

Local insect allergen extracts skin test

Intervention Type DIAGNOSTIC_TEST

Every patient received both local and commercial insect allergen extracts but in blinded methods

Interventions

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Local insect allergen extracts skin test

Every patient received both local and commercial insect allergen extracts but in blinded methods

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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commercial insect allergen extracts from ALK skintest

Eligibility Criteria

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Inclusion Criteria

* Patients with severe insect allergy reaction
* Allow being done skin test and blood foe specific IgE

Exclusion Criteria

* Serious systemic diseases
* severe asthma
* pregnant or nursing
* severe and extended skin lesion
Minimum Eligible Age

5 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mahidol University

OTHER

Sponsor Role lead

Responsible Party

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Nualanong Visitsunthorn

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nualanong Visitsunthorn, MD

Role: PRINCIPAL_INVESTIGATOR

Siriraj Hospital

Locations

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Siriraj hospital

Bangkok, , Thailand

Site Status

Countries

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Thailand

Other Identifiers

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450/2559 (EC 3)

Identifier Type: -

Identifier Source: org_study_id

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