Effect of Plasma Rich in Growth Factors on Semen Quality

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-04-30

Study Completion Date

2017-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The hypothesis is growing semen samples with plasma rich in growth factors (PRGF), because it could improve sperm motility in patients subsidiary TRA, ultimately improving pregnancy rates.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Effects of Autologous Platelet-rich Plasma Supplement During Sperm Cryopreservation on Post-cryopreserved Sperm Quality

NCT06258759

Autologous Platelet-rich Plasma Supplement Sperm Cryopreservation Post-cryopreserved Sperm Quality +1 more

RECRUITING NA

Platelet Rich Plasma Testis Treatment for Infertile Men

NCT05479474

Male Infertility Nonobstructive Azoospermia Azoospermia

RECRUITING NA

A Retrospective Study on the Effect of Male Progressive Sperm Count After Semen Pretreatment on ICSI Fertilization Outcome

NCT03594201

Sperm Count, Low Reproductive Sterility

COMPLETED

The Effects of Microgravity on Human Sperm

NCT03760783

Semen Quality

COMPLETED NA

Regulation of Stem Spermatogonia in the Mature Testis

NCT02756923

Male Infertility

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Platelet growth factors are a group of proteins involved in cellular communication modifying biological responses. Obtaining plasma rich in growth factors is already widespread and simple protocol technique that is being used in various areas of medicine with superb results. Described many of the growth factors present in the PRGF are related to sperm parameters, especially motility The described effects have been studied in mammalian and each growth factor individually. PRGF contains a pool of growth factors and therefore be interesting to analyze their effect on various sperm parameters.

One of those parameters is very important for fertilization sperm motility, since the lack of it will prevent displacement by the cervix to meet the egg in the fallopian tube.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Vascular Endothelial Growth Factor Overexpression

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

PRGF in candidates for sperm donors

Prospective study of 58 candidates for sperm donors clinic IVI Bilbao.

PRGF in candidates for sperm donors

Intervention Type BIOLOGICAL

PRGF application on seminal aliquots will be conducted at different concentrations assessing sperm motility.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

PRGF in candidates for sperm donors

PRGF application on seminal aliquots will be conducted at different concentrations assessing sperm motility.

Intervention Type BIOLOGICAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 18-35 years
* more than 5 million sperm per milliliter

Exclusion Criteria

* Not having genetic and infectious diseases
* Do not suffer mental illness
* Have a family study determined that there is no risk of hereditary diseases
* There have fathered more than 6 children in the country

Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes