Optimization of Interval-training in Patients With Type 2 Diabetes

NCT ID: NCT02601482

Last Updated: 2016-06-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-10-31

Study Completion Date

2016-10-31

Brief Summary

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A single bout of Interval-Walking (IW) exercise is superior to energy-expenditure and time-duration matched Continuous Walking (CW) exercise upon improving glycemic control. The time spend with high-intensity (fast) walking is considered to be responsible for the improvements seen, whereas the time spend with low-intensity (slow) walking is considered less important.

This study will assess if IW with maintained fast walking time duration but reduced total time duration (i.e. reduced slow walking time duration) is equally effective as IW with a normal time duration.

Subjects with type 2 diabetes will be included in a crossover, controlled study, where each subject will undergo three trials. Trials will be identical except the following interventions:

1. Sixty minutes of rest (CON)
2. Sixty minutes of classical interval walking (repeated cycles of 3 minutes of fast and 3 minutes of slow walking; IW-60)
3. Fourty-five minutes of time-reduced interval walking (repeated cycles of 3 minutes of fast and 1.5 minutes of slow walking; IW-45).

After the interventions subjects will undergo a standardized mixed meal tolerance test with assessment of glycemic control.

Detailed Description

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Conditions

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Diabetes Mellitus, Type 2

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Control (CON)

No exercise intervention.

Group Type EXPERIMENTAL

CON

Intervention Type BEHAVIORAL

Normal Interval Walking (IW-60).

Sixty minutes with repeated cycles of 3 minutes of fast and 3 minutes of slow walking on a treadmill

Group Type EXPERIMENTAL

IW-60

Intervention Type BEHAVIORAL

Time-reduced Interval Walking (IW-45)

Forty-five minutes with repeated cycles of 3 minutes of fast and 1.5 minutes of slow walking on a treadmill

Group Type EXPERIMENTAL

IW-45

Intervention Type BEHAVIORAL

Interventions

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CON

Intervention Type BEHAVIORAL

IW-60

Intervention Type BEHAVIORAL

IW-45

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Type 2 Diabetes Mellitus
* BMI \> 25

Exclusion Criteria

* Pregnancy
* Smoking
* Contraindication to increased levels of physical activity
* Eating disorder
* Insulin dependence
Minimum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Rigshospitalet, Denmark

OTHER

Sponsor Role lead

Responsible Party

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Anders Rasmussen Rinnov

MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Center for Physical Activity Research (CFAS)

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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H-15008542 - 2

Identifier Type: -

Identifier Source: org_study_id

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