The Features Behind the Beneficial Effects of Interval-walking
NCT ID: NCT02257190
Last Updated: 2015-10-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
12 participants
INTERVENTIONAL
2014-10-31
2015-10-31
Brief Summary
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This study will look into whether it is the larger peak intensity during IW or if it is the alternating exercise pattern that is responsible for the larger improvements seen.
Subjects with type 2 diabetes will be included in a crossover, counter-balanced, controlled study, where each subject will undergo three trials. Trials will be identical except the following interventions:
1. One hour of rest (Con)
2. One hour of classical interval walking (repeated cycles of 3 min of fast and 3 min of slow walking; IW3)
3. One hour of fast alternating interval walking (repeated cycles of 1 min of fast and 1 min of slow walking; IW1).
After the interventions subjects will undergo a standardized mixed meal tolerance test, with consecutive measurements of blood glucose, insulin and c-peptide.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
NONE
Study Groups
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Control (Con)
No exercise intervention.
Control
One hour of rest.
Interval Walking - 3 min intervals (IW3)
One hour of classical interval walking exercise (repeated cycles of 3 min of fast and 3 min of slow walking.
IW3
A one hour exercise bout with repeated cycles of 3 min of fast and 3 min of slow walking
Interval Walking - 1 min intervals (IW1)
One hour of fast alternating interval walking exercise (repeated cycles of 3 min of fast and 3 min of slow walking
IW1
A one hour exercise bout with repeated cycles of 1 min of fast and 1 min of slow walking
Interventions
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Control
One hour of rest.
IW3
A one hour exercise bout with repeated cycles of 3 min of fast and 3 min of slow walking
IW1
A one hour exercise bout with repeated cycles of 1 min of fast and 1 min of slow walking
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Body mass index \> 18 but \< 40 m2/kg
* Agreement to pause antidiabetic medication from 2 days before to after each trial
Exclusion Criteria
* Smoking
* Use of exogenous insulin
* Contraindication to increased levels of physical activity
* Evidence of thyroid, liver, lung, heart or kidney disease
30 Years
ALL
No
Sponsors
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Rigshospitalet, Denmark
OTHER
Responsible Party
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Anders Rasmussen Rinnov
MD, PhD
Principal Investigators
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Kristian Karstoft, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Centre for Physical Activity Research, Rigshospitalet, Denmark
Locations
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Center for Physical Activity Research (CFAS)
Copenhagen, , Denmark
Countries
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References
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Jakobsen I, Solomon TP, Karstoft K. The Acute Effects of Interval-Type Exercise on Glycemic Control in Type 2 Diabetes Subjects: Importance of Interval Length. A Controlled, Counterbalanced, Crossover Study. PLoS One. 2016 Oct 3;11(10):e0163562. doi: 10.1371/journal.pone.0163562. eCollection 2016.
Other Identifiers
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H-1-2014-060
Identifier Type: -
Identifier Source: org_study_id
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