Comparing Nd:YAG Laser and Sequential Double Frequency YAG-Nd:YAG Laser Iridotomy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

82 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-05-31

Study Completion Date

2018-08-31

Brief Summary

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No single type of laser or set of laser parameters is appropriate for all type of irides. Pure Nd:YAG laser iridotomy is very effective in the light color irides. It was considered as the gold standard for iridotomy. It, however, is less effective and causes some complication such as iris hemorrhage especially in patients with dark iris.

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Detailed Description

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By using the double frequency YAG to make the initial bore and the Nd:YAG laser to complete the perforation, the technique should be able to effectively combine most of the advantages of both lasers whilst avoiding their disadvantages. It is possibly the ideal iridotomy technique to use in the Asian irides. The investigators aim to study the energy use for laser iridotomy comparing between the two techniques as well as objectively measure the variables associated with complications.

Conditions

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Angle Closure Glaucoma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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The sequential technique

By using the double frequency YAG laser to make the initial bore and the Nd:YAG laser to complete the perforation on iris.

Group Type EXPERIMENTAL

The sequential technique

Intervention Type DEVICE

By using 'the double frequency YAG laser' to make the initial bore and 'the Nd:YAG laser' to complete the perforation on iris.

The pure Nd:YAG laser technique

By using the pure Nd:YAG to make a complete perforation on iris.

Group Type ACTIVE_COMPARATOR

The pure Nd:YAG laser technique

Intervention Type DEVICE

By using 'the pure Nd:YAG laser' to make a complete perforation on iris.

Interventions

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The sequential technique

By using 'the double frequency YAG laser' to make the initial bore and 'the Nd:YAG laser' to complete the perforation on iris.

Intervention Type DEVICE

The pure Nd:YAG laser technique

By using 'the pure Nd:YAG laser' to make a complete perforation on iris.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patient in need to have a laser iridotomy

* primary angle closure glaucoma or
* primary angle closure or
* primary angle closure suspect (needed repeated pupil dilation) or
* fellow eyes of acute angle closure crisis, and
* Age of at least 18 years, and
* Dark iris patients (only black and dark brown color)

Exclusion Criteria

* Eye with acute angle closure crisis
* Active conjunctiva or corneal infection or inflammation
* Active anterior uveitis
* History of any prior laser treatment
* History intraocular surgery
* Eye with corneal scar
* Corneal haziness obscure iridotomy site
* Endothelial cell count less than 1000 cells/mm2 (pre-laser)
* Iris color other than black or dark brown
* Inability to sit at the slit lamp to have laser done

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No