Inflammatory Gene Polymorphism and Prolonged Mechanical Ventilation After Liver Transplantation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

141 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-01-31

Study Completion Date

2018-01-08

Brief Summary

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Mechanical ventilatory lung care is essential for postoperative care in liver transplantation recipients, for such patients are under massive fluid challenge and hemodynamic alterations perioperatively. Some of the recipients experience difficulty in weaning off from the mechanical ventilator due to various causes. This study is to investigate the relationship between the inflammatory gene polymorphism, known for acute lung injury, and the duration of mechanical ventilatory care for such liver transplantation recipients.

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Detailed Description

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Conditions

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Patients With Postoperative Mechanical Ventilation After Liver Transplantation

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Mechanical ventilatory lung care

liver transplantation recipients under mechanical ventilatory lung care

Mechanical ventilatory lung care

Intervention Type OTHER

Interventions

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Mechanical ventilatory lung care

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. 20-65 years old
2. scheduled for liver transplantation

Exclusion Criteria

1. Patients under mechanical ventilation prior to surgery
2. patients with muscular skeletal disorder, probable cause for respiratory depression
3. patients not able to read, or understand the consent form
4. ethnicity, other than asian
5. patients refusal

Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes