Lung Protective Ventilation During Pulmonary Lobectomy in Children
NCT ID: NCT02680925
Last Updated: 2018-03-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
114 participants
INTERVENTIONAL
2016-02-29
2018-02-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
DOUBLE
Study Groups
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Conventional ventilation group
Mechanical ventilation is maintained with tidal volume (TV) of 10 ml/kg without PEEP during two-lung ventilation and TV of 8 ml/kg without PEEP during one-lung ventilation. Alveolar recruitment is performed 3 times; after intubation, before one-lung ventilation and after lung resection.
Conventional ventilation
TV 8 ml/kg during one lung ventilation and 10 ml/kg during two-lung ventilation without PEEP
Lung protective ventilation group
Mechanical ventilation is maintained with tidal volume (TV) of 6 ml/kg with PEEP 6 cmH2O during two-lung ventilation and TV of 4 ml/kg PEEP 6 cmH2O during one-lung ventilation. Alveolar recruitment is performed 3 times; after intubation, before one-lung ventilation and after lung resection.
lung protective ventilation
TV 4 ml/kg during one lung ventilation and 6 ml/kg during two-lung ventilation with PEEP of 6 cmH2O
Interventions
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lung protective ventilation
TV 4 ml/kg during one lung ventilation and 6 ml/kg during two-lung ventilation with PEEP of 6 cmH2O
Conventional ventilation
TV 8 ml/kg during one lung ventilation and 10 ml/kg during two-lung ventilation without PEEP
Eligibility Criteria
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Inclusion Criteria
* ASA physical status I, II
Exclusion Criteria
* Active URI
* Systemic inflammatory response disease
* cardiac disease
5 Years
ALL
No
Sponsors
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Seoul National University Hospital
OTHER
Responsible Party
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Jin-Tae Kim
Associate professor
Principal Investigators
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Jin-Tae Kim, PhD
Role: PRINCIPAL_INVESTIGATOR
Seoul National University Hospital
Locations
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Seoul national university hospital
Seoul, , South Korea
Countries
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References
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Lee JH, Bae JI, Jang YE, Kim EH, Kim HS, Kim JT. Lung protective ventilation during pulmonary resection in children: a prospective, single-centre, randomised controlled trial. Br J Anaesth. 2019 May;122(5):692-701. doi: 10.1016/j.bja.2019.02.013. Epub 2019 Mar 8.
Other Identifiers
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H1511-124-725
Identifier Type: -
Identifier Source: org_study_id
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