Optisure Lead Post Approval Study

NCT ID: NCT02235545

Last Updated: 2025-07-30

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

1735 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-08-31

Study Completion Date

2020-06-30

Brief Summary

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The purpose of this post approval study is to characterize the chronic performance of the SJM Optisure family of HV leads in patients.

Detailed Description

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The Optisure lead study is a multi-center, post-approval study that will be performed in compliance with the Conditions for Approval, as agreed upon with the FDA. Patients will be permitted to enroll in the study up to 30 days post-implant of the Optisure lead. Following a successful implant, patients will be followed every 6 months until 60 months (5 years). After patients complete 60 months of follow-up, their participation in the study will end. Patients who are consented prior to implant and for whom an implant is unsuccessful will be followed for 30 days for any adverse events and then withdrawn from the study, or may have an implant reattempted if the physician and patient choose to do so.

Conditions

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Heart Failure Tachycardia, Ventricular

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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St. Jude Medical Optisure Lead

Patients implanted with St. Jude Medical Optisure Lead

St. Jude Medical Optisure Lead

Intervention Type DEVICE

Patients implanted with St. Jude Medical Optisure Lead

Interventions

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St. Jude Medical Optisure Lead

Patients implanted with St. Jude Medical Optisure Lead

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

Eligible patients will meet all of the following:

1. Have an approved indication, as per ACC/AHA/HRS/ESC guidelines, for implantation of an ICD or CRT-D system for treatment of heart failure or life-threatening ventricular tachyarrhythmia(s).
2. Have been implanted with a St. Jude Medical Optisure lead in the last 30 days or are scheduled for an Optisure lead implant.
3. Have the ability to provide informed consent for study participation and be willing and able to comply with the prescribed follow-up tests and schedule of evaluations.
4. Are 18 years or above, or of legal age to give informed consent specific to state and national law.

Exclusion Criteria

Patients will be excluded if they meet any of the following:

1. Enrolled or intend to participate in a clinical drug and/or device study, which could confound the results of this trial as determined by SJM, during the course of this clinical study.
2. Have a life expectancy of less than 5 years due to any condition.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abbott Medical Devices

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Nicole Harbert

Role: STUDY_DIRECTOR

Abbott

Locations

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Baptist Medical Center Princeton

Birmingham, Alabama, United States

Site Status

Phoenix Cardiovascular Research Group

Phoenix, Arizona, United States

Site Status

St. Bernards (formerly Cardiology Associates of Northeast Arkansas)

Jonesboro, Arkansas, United States

Site Status

Raymond Schaerf, MD

Burbank, California, United States

Site Status

Desert Heart Rhythm Consultants

Palm Springs, California, United States

Site Status

Cardiac Rhythm Specialists, Inc.

Reseda, California, United States

Site Status

San Diego Heart Rhythm Center (formerly San Diego Heart and Vascular Associates)

San Diego, California, United States

Site Status

Jorge Diaz, M.D. , P.A.

Lake Mary, Florida, United States

Site Status

Northside Hospital

Atlanta, Georgia, United States

Site Status

Rockford Cardiology Associates

Rockford, Illinois, United States

Site Status

Parkview Research Center

Fort Wayne, Indiana, United States

Site Status

Iowa Heart Center

West Des Moines, Iowa, United States

Site Status

St. Elizabeth Medical Center - South Unit

Edgewood, Kentucky, United States

Site Status

Peninsula Cardiology Associates

Salisbury, Maryland, United States

Site Status

Mass Heart & Rhythm

Leominster, Massachusetts, United States

Site Status

Premier Medical Clinics

Flint, Michigan, United States

Site Status

Genesys Regional Medical Center

Grand Blanc, Michigan, United States

Site Status

Northern Michigan Hospital

Traverse City, Michigan, United States

Site Status

Minneapolis Heart Institute

Minneapolis, Minnesota, United States

Site Status

Jackson Heart Clinic

Jackson, Mississippi, United States

Site Status

Cardiology Associates of North Mississippi

Tupelo, Mississippi, United States

Site Status

HealthCare Partners Cardiology

Las Vegas, Nevada, United States

Site Status

Cardiovascular Associates of the Delaware Valley

Haddon Heights, New Jersey, United States

Site Status

Lourdes Cardiology Services

Voorhees Township, New Jersey, United States

Site Status

Presbyterian Heart Group

Albuquerque, New Mexico, United States

Site Status

Maimonides Medical Center

Brooklyn, New York, United States

Site Status

Coney Island Hospital

Brooklyn, New York, United States

Site Status

Cardiovascular Group of Syracuse

Liverpool, New York, United States

Site Status

High Point Regional Health (formerly Carolina Cardiology Cornerstone)

High Point, North Carolina, United States

Site Status

CarolinaEast Heart Center

New Bern, North Carolina, United States

Site Status

VA Medical Center Cleveland

Cleveland, Ohio, United States

Site Status

Great Lakes Medical Research, LLC

Willoughby, Ohio, United States

Site Status

Integris Baptist Medical Center

Oklahoma City, Oklahoma, United States

Site Status

Providence Heart and Vascular Institute

Portland, Oregon, United States

Site Status

Lehigh Valley Hospital

Allentown, Pennsylvania, United States

Site Status

Lancaster General Hospital

Lancaster, Pennsylvania, United States

Site Status

Arrhythmia Institute

Newtown, Pennsylvania, United States

Site Status

The Stern Cardiovascular Foundation

Germantown, Tennessee, United States

Site Status

HeartPlace

Bedford, Texas, United States

Site Status

VA Medical Center Dallas

Dallas, Texas, United States

Site Status

Cardiology Care Consultants

El Paso, Texas, United States

Site Status

Scott & White Memorial Hospital

Temple, Texas, United States

Site Status

Heart of Dixie Cardiology (formerly Dixie Regional Medical Center - River Road Campus)

St. George, Utah, United States

Site Status

Mary Washington Hospital

Fredericksburg, Virginia, United States

Site Status

Virginia Cardiovascular Specialists

Richmond, Virginia, United States

Site Status

Aurora Medical Group

Milwaukee, Wisconsin, United States

Site Status

Ziekenhuis Oost-Limburg

Genk, Limburg, Belgium

Site Status

Royal Alexandra Hospital

Edmonton, Alberta, Canada

Site Status

St. Boniface General Hospital

Winnipeg, Manitoba, Canada

Site Status

QE II Health Sciences

Halifax, Nova Scotia, Canada

Site Status

Kingston General Hospital

Kingston, Ontario, Canada

Site Status

London Health Sciences Centre

London, Ontario, Canada

Site Status

Rouge Valley Centenary

Scarborough Village, Ontario, Canada

Site Status

Institut de Cardiologie de Montreal (Montreal Heart Inst.)

Montreal, Quebec, Canada

Site Status

Universitäts-Herzzentrum Freiburg - Bad Krozingen

Bad Krozingen, , Germany

Site Status

Tokyo Women's Medical University

Shinjuku-Ku, Kanto, Japan

Site Status

Osaka City University Hospital

Abeno-ku, Osaka, Japan

Site Status

Jichi Medical University Hospital

Shimotsuke-shi, Tochigi, Japan

Site Status

Mc-Tronik

Lodz, , Poland

Site Status

Santa Maria Hospital

Lisbon, Lisbon District, Portugal

Site Status

Countries

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United States Belgium Canada Germany Japan Poland Portugal

Provided Documents

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Document Type: Study Protocol

View Document

Other Identifiers

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60045220

Identifier Type: -

Identifier Source: org_study_id

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