APART: Prevention and Automatic Therapy of Atrial Arrhythmias in Patients With Paroxysmal Supraventricular Tachycardias

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

156 participants

Study Classification

INTERVENTIONAL

Study Start Date

2000-08-31

Study Completion Date

2014-10-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of APART is the assessment of the therapeutic and preventive stimulation algorithms of the Medtronic AT500 and following devices in patients with atrial tachyarrhythmias and an indication for cardiac pacing according to the German guidelines. Medication is controlled throughout the study with a beta-blocker as the only antiarrhythmic drug.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Arrhythmia Restart Prevention and RatE STabilization in Atrial Fibrillation

NCT00224341

Sick Sinus Syndrome Brady-Tachy Syndrome

UNKNOWN PHASE4

ABLATE Versus PACE: PVI or AV Node Ablation and PM Implantation for Elderly Patients With Persistent AF

NCT04906668

Atrial Fibrillation

ACTIVE_NOT_RECRUITING NA

Ablation of the Pulmonary Veins for Paroxysmal Afib

NCT00744874

Paroxysmal Atrial Fibrillation

COMPLETED PHASE4

AF Septal Pacing (Clinical Investigation Plan)

NCT03242941

Paroxysmal Atrial Fibrillation Persistent Atrial Fibrillation

COMPLETED NA

Burst Stimulation for Paroxysmal Atrial Fibrillation

NCT07281898

Paroxysmal Atrial Fibrillation

RECRUITING NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Tachyarrhythmia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Control Arm

Algorithms for prevention and termination of AF not activated

Group Type NO_INTERVENTION

No interventions assigned to this group

Prevention and Therapy Algorithms on

Activation of preventive and therapeutic algorithms

Group Type ACTIVE_COMPARATOR

Activation of preventive and therapeutic algorithms for treatment of AF

Intervention Type DEVICE

Algorithms in At 500 or Enrhyhtm for prevention and termination of Atrial Fibrillation

AF Prevention and Therapy Algorithms On

Intervention Type DEVICE

Activation of AF-prevention and termination algorithms in AT 500 or EnRhyhtm

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Activation of preventive and therapeutic algorithms for treatment of AF

Algorithms in At 500 or Enrhyhtm for prevention and termination of Atrial Fibrillation

Intervention Type DEVICE

AF Prevention and Therapy Algorithms On

Activation of AF-prevention and termination algorithms in AT 500 or EnRhyhtm

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Indication for cardiac pacing according to the German guidelines
* Documented (electrocardiogram; ECG) atrial arrhythmia during the last three months before enrollment
* Willingness to terminate antiarrhythmic drugs until the first recurrence of an atrial arrhythmia
* Sinus rhythm during 24 hours before implant of the device

Exclusion Criteria

* Ejection fraction below 40%
* Mechanic prosthesis of the tricuspid valve
* Indication to implantable cardioverter defibrillator (ICD)-implantation
* Pregnancy

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No