Serial Measurement of Capillary Blood Lactate in the Management of Sepsis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-02-28

Study Completion Date

2017-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Determination of capillary lactate by using "point-of-care" technique is accessible, fast and allows to quantify the circulatory and metabolic dysfunction caused by sepsis. Compared to conventional assay techniques in arterial blood, capillary assay technique may have an increased susceptibility to metabolic alterations induced by sepsis in its initial stages. This increased sensitivity is not necessarily relevant in the management of the most serious patients for whom the diagnosis is obvious, but it could be very useful in patients for whom a diagnosis of severe sepsis or shock have not yet been adopted, particularly to help better identify patients who would require intensive management and avoid the installation of these serious disorders.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Lactate Use as Triage Tool in Sepsis : Veinous, Capillary or Arterial?

NCT01964690

Sepsis

COMPLETED

Blood Lactate Level for Pre-hospital Orientation of Septic Shock

NCT03831685

Sepsis Lactate Blood Increase

UNKNOWN

Study of Subcutaneous Interstitial Pressure During Sepsis

NCT03818269

Patients with Septic Shock

COMPLETED NA

Early Lactate Clearance Rate in Sepsis

NCT04192279

Early Lactate Clearance

UNKNOWN

Lactate Metabolism After an Endotoxin Challenge in Healthy Humans

NCT01647997

Sepsis

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Sepsis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

OTHER

Study Time Perspective

OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age ≥ 18 years
* Installation without any plausible explanation of at least one of the following clinical criteria:

* Chills, fever, mottling, respiratory rate\> 20/min; Sat02 \< 90% or \> 94% with more than 4l O2, heart rate \> 90/min,systolic blood pressure \< 100 mmHg or 40 mmHg lower compared with normal values, Glasgow coma score \< 14. or: .a combination of two (or more) of clinical and laboratory criteria for sepsis.
* Signed informed consent form

Exclusion Criteria

* Need in its current treatment of aerosol administration of beta agonists at a frequency greater than one per 8 hours;
* Targeted therapeutic measures have already stated for more than 60 minutes;
* Diagnosis other than Sepsis;
* Malignant neoplasm or other progressive disease and expected survival was less than 3 months.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No