The Prognostic Value of Lactate is Different Among Septic Patients
NCT ID: NCT04155060
Last Updated: 2020-07-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
256 participants
OBSERVATIONAL
2017-04-01
2019-04-01
Brief Summary
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Detailed Description
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Currently, lactate is widely applied as the marker for evaluating the severity of sepsis and for outcome predicting.Nevertheless, the value of lactate for predicting sepsis is still controversial.The reasons for the different cutoff value may be due to the fact that sepsis is a heterogeneous disease which has already been defined by a number of clinical, laboratory and radiologic criteria, rather than specific pathologic findings. Therefore, we hypothesized that the discrepancy clinical value of lactate may be resulted from the heterogeneous feature of sepsis.
DM affects lactate balance and raised baseline lactate. The objective of this study was to compare the different prognostic value of admission lactate for sepsis patients with or without DM.
Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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DM group , non-DM group
Septic patients were divided into the DM group and non-DM group, based on their comorbidity
No interventions assigned to this group
high lactate group,low lactate group
high lactate group (lactate \> 2 mmol/L) and low lactate group (lactate ≤ 2 mmol/L), according to the admission lactate level.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
100 Years
ALL
No
Sponsors
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Shanghai Zhongshan Hospital
OTHER
Responsible Party
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Locations
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180 Fenglin Road
Shanghai, Shanghai Municipality, China
Countries
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Other Identifiers
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PROMPT
Identifier Type: -
Identifier Source: org_study_id
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