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Thromboelastometry in Assessment of Sepsis Coagulopathy

NCT ID: NCT02971111

Last Updated: 2018-09-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

76 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-01-31

Study Completion Date

2016-10-31

Brief Summary

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The purpose of this study is to analyze occurence of bleeding complications during invasive procedures in septic patients with normal tromboelastometry results despite prolonged standard coagulation tests results

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Detailed Description

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Conditions

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Thrombelastography Sepsis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* sepsis/septic shock
* prolonged PT-INR (international normalized ratio) ≥ 1.3
* normal ROTEM-EXTEM results.

Exclusion Criteria

* patients on antiplatelet drugs or anticoagulant therapy (heparin, vitamin K antagonists…)
* patients with cirrhosis
Minimum Eligible Age

24 Years

Maximum Eligible Age

89 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Charles University, Czech Republic

OTHER

Sponsor Role collaborator

University Hospital, Motol

OTHER

Sponsor Role lead

Responsible Party

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Durila Miroslav MUDr. Ph.D.

clinical researcher

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Lukas P, Durila M, Jonas J, Vymazal T. Evaluation of Thromboelastometry in Sepsis in Correlation With Bleeding During Invasive Procedures. Clin Appl Thromb Hemost. 2018 Sep;24(6):993-997. doi: 10.1177/1076029617731624. Epub 2017 Sep 26.

Reference Type DERIVED
PMID: 28950719 (View on PubMed)

Other Identifiers

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1318514

Identifier Type: -

Identifier Source: org_study_id

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