Effects of Transcutaneous Electrical Nerve Stimulation on Cortical Excitability in the Primary Motor Cortex in Healthy Adults

NCT ID: NCT02077595

Last Updated: 2014-03-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-01-31

Study Completion Date

2013-07-31

Brief Summary

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Recently, non-invasive brain stimulation has become a powerful tool in both basic research and clinical application. Among several non-invasive brain stimulation techniques, transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have received the most attention. About DC stimulation, the change of polarity could modulate the spontaneous neuronal activity and make effect on decision making, language, memory, sensory perception, and pain. In spite of that the concept of transcranial alternating current stimulation (tACS) is not novel, AC is relatively safe compared to DC, and researches have revealed that AC might potentially have the effect on the cortical excitability. However, there are still many areas about AC stimulation which remain unknown, such as mechanism, application, and potential influence on cortical excitability.

Detailed Description

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Conditions

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Transcutaneous Electrical Nerve Stimulation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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120Hz alternating current stimulation group

Group Type ACTIVE_COMPARATOR

transcutaneous electrical nerve stimulation, TENS

Intervention Type DEVICE

Then participants will receive stimulation for 20 minutes.

5Hz alternating current stimulation group

Group Type ACTIVE_COMPARATOR

transcutaneous electrical nerve stimulation, TENS

Intervention Type DEVICE

Then participants will receive stimulation for 20 minutes.

sham alternating current stimulation group

Group Type SHAM_COMPARATOR

transcutaneous electrical nerve stimulation, TENS

Intervention Type DEVICE

Then participants will receive stimulation for 20 minutes.

Interventions

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transcutaneous electrical nerve stimulation, TENS

Then participants will receive stimulation for 20 minutes.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Healthy adults
Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Chang Gung University

OTHER

Sponsor Role lead

Responsible Party

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Ya-Ju Chang

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Chang Gung University

Taoyuan District, , Taiwan

Site Status

Countries

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Taiwan

Other Identifiers

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101-3624B

Identifier Type: -

Identifier Source: org_study_id

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