Reversal of General Anesthesia With Methylphenidate

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1/PHASE2

Total Enrollment

32 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-11-30

Study Completion Date

2018-05-31

Brief Summary

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The aim of this study is to investigate whether methylphenidate (Ritalin) can actively induce emergence from general anesthesia in patients having a pancreaticoduodenectomy (Whipple procedure), a pancreatectomy, or a prostatectomy.

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Detailed Description

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Conditions

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Post Operative Cognitive Dysfunction Emergence From Anesthesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Methylphenidate

Group Type EXPERIMENTAL

Methylphenidate

Intervention Type DRUG

placebo

Saline

Group Type PLACEBO_COMPARATOR

Saline

Intervention Type OTHER

Interventions

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Methylphenidate

Intervention Type DRUG

Saline

Intervention Type OTHER

Other Intervention Names

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ritalin

Eligibility Criteria

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Inclusion Criteria

* Age 18-75 years
* American Society of Anesthesiologists classification 1 or 2
* Scheduled to undergo a pancreaticoduodenectomy or distal pancreatectomy at Massachusetts General Hospital