Effect of the Transmuscular Quadratus Lumborum Block on Duration of Stay in Recovery

NCT ID: NCT04951752

Last Updated: 2021-07-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

307 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-04-14

Study Completion Date

2021-08-01

Brief Summary

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The study will review data collected in 5 previously completed randomised controlled trials with a new primary outcome: to assess whether administration of the transmuscular quadratus lumborum block has an impact on the time an individual patient stays in the postanaesthesia care unit and how much opioid is consumed during this specified time.

Detailed Description

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Conditions

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Anesthesia, Local

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Hemicolectomy, Active treatment

2x30mL 0.375% Ropivacaine administered by way of transmuscular quadratus lumborum block

Ropivacaine injection

Intervention Type DRUG

Transmuscular quadratus lumborum block - active

Hemicolectomy, Placebo treatment

2x30mL isotonic saline administered by way of transmuscular quadratus lumborum block

No interventions assigned to this group

Nephrectomy, Active treatment

2x30mL 0.375% Ropivacaine administered by way of transmuscular quadratus lumborum block

Ropivacaine injection

Intervention Type DRUG

Transmuscular quadratus lumborum block - active

Nephrectomy, Placebo treatment

2x30mL isotonic saline administered by way of transmuscular quadratus lumborum block

No interventions assigned to this group

Percutaneous nephrolithotomy, Active treatment

1x30mL 0.75% Ropivacaine administered by way of transmuscular quadratus lumborum block

Ropivacaine injection

Intervention Type DRUG

Transmuscular quadratus lumborum block - active

Percutaneous nephrolithotomy, Placebo treatment

1x30mL isotonic saline administered by way of transmuscular quadratus lumborum block

No interventions assigned to this group

Hysterectomy, Active treatment

2x30mL 0.375% Ropivacaine administered by way of transmuscular quadratus lumborum block

Ropivacaine injection

Intervention Type DRUG

Transmuscular quadratus lumborum block - active

Hysterectomy, Placebo treatment

2x30mL isotonic saline administered by way of transmuscular quadratus lumborum block

No interventions assigned to this group

Elective Caesarean section, Active treatment

2x30mL 0.375% Ropivacaine administered by way of transmuscular quadratus lumborum block

Ropivacaine injection

Intervention Type DRUG

Transmuscular quadratus lumborum block - active

Elective Caesarean section, Placebo treatment

2x30mL isotonic saline administered by way of transmuscular quadratus lumborum block

No interventions assigned to this group

Interventions

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Ropivacaine injection

Transmuscular quadratus lumborum block - active

Intervention Type DRUG

Other Intervention Names

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Transmuscular quadratus lumborum block

Eligibility Criteria

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Inclusion Criteria

\- Elective Surgery

Exclusion Criteria

* Inability to cooperate
* Allergy to local anaesthetics or opioids
* Inability to understand Danish
* Regular intake of opioids
* Local infection at site of injection
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zealand University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jens Børglum Neimann, MD, PhD

Role: STUDY_DIRECTOR

Associate Professor, Zealand University Hospital

Locations

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Zealand University Hospital

Roskilde, , Denmark

Site Status

Countries

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Denmark

References

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Dam M, Hansen C, Poulsen TD, Azawi NH, Laier GH, Wolmarans M, Chan V, Bendtsen TF, Borglum J. Transmuscular quadratus lumborum block reduces opioid consumption and prolongs time to first opioid demand after laparoscopic nephrectomy. Reg Anesth Pain Med. 2021 Jan;46(1):18-24. doi: 10.1136/rapm-2020-101745. Epub 2020 Oct 26.

Reference Type BACKGROUND
PMID: 33106280 (View on PubMed)

Hansen CK, Dam M, Steingrimsdottir GE, Laier GH, Lebech M, Poulsen TD, Chan VWS, Wolmarans M, Bendtsen TF, Borglum J. Ultrasound-guided transmuscular quadratus lumborum block for elective cesarean section significantly reduces postoperative opioid consumption and prolongs time to first opioid request: a double-blind randomized trial. Reg Anesth Pain Med. 2019 Jul 14:rapm-2019-100540. doi: 10.1136/rapm-2019-100540. Online ahead of print.

Reference Type BACKGROUND
PMID: 31308263 (View on PubMed)

Dam M, Hansen CK, Poulsen TD, Azawi NH, Wolmarans M, Chan V, Laier GH, Bendtsen TF, Borglum J. Transmuscular quadratus lumborum block for percutaneous nephrolithotomy reduces opioid consumption and speeds ambulation and discharge from hospital: a single centre randomised controlled trial. Br J Anaesth. 2019 Aug;123(2):e350-e358. doi: 10.1016/j.bja.2019.04.054. Epub 2019 May 30.

Reference Type RESULT
PMID: 31153628 (View on PubMed)

Other Identifiers

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SOPRE-001

Identifier Type: -

Identifier Source: org_study_id

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