Adductor Canal Block With Continuous Infusion Versus Intermittent Boluses and Morphine Consumption

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

110 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-03-31

Study Completion Date

2016-09-30

Brief Summary

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The investigators believe sufficient spread to all nerves within the adductor canal-and thereby sufficient analgesia-can only be obtained by bolus injections and not by continuous infusions via a catheter. The aim of the study is to investigate whether an adductor canal block performed as repeated intermittent boluses provides superior pain relief to continuous infusion. The investigators hypothesize that adductor canal block performed as intermittent boluses via a catheter will reduce morphine consumption and pain as well as enhance ambulation and muscle strength compared with continuous infusion.

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Detailed Description

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Conditions

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Postoperative Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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Intermittent bolus

ropivacaine 0.2%, 21 ml every 3 hours

Group Type EXPERIMENTAL

ropivacaine 0.2%

Intervention Type DRUG

Adductor canal block. Placed immediately postoperative. Intervention stops on POD2 12PM

Continuous infusion

ropivacaine 0.2%, 7ml/h

Group Type ACTIVE_COMPARATOR

ropivacaine 0.2%

Intervention Type DRUG

Adductor canal block. Placed immediately postoperative. Intervention stops on POD2 12PM

Interventions

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ropivacaine 0.2%

Adductor canal block. Placed immediately postoperative. Intervention stops on POD2 12PM

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients scheduled for total knee arthroplasty in spinal anesthesia
* Patients who gave their written informed consent to participating in the study after having fully understood the contents of the protocol and restrictions
* American society of anesthesiologists 1-3
* Ability to perform a timed up and go test preoperatively

Exclusion Criteria

* Patients who cannot cooperate
* Patients who cannot understand or speak Danish.
* Patients with allergy to the medicines used in the study
* Patients with a daily intake of strong opioids (morphine, oxycodone, ketobemidone, methadone, fentanyl) during the last 4 weeks
* Patients suffering from alcohol and/or drug abuse - based on the investigator's assessment
* Rheumatoid arthritis
* BMI \> 40
* Neuromuscular pathology in the lower limbs
* Pregnancy

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No