Aerobic Exercise on Improving Sleep in Systemic Lupus Erythematosus.

NCT ID: NCT02037971

Last Updated: 2014-01-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-02-28

Study Completion Date

2015-03-31

Brief Summary

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The purpose of this study is to determine the effectiveness of exercise training on improving sleep in patients with systemic lupus erythematosus.

Detailed Description

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This study will test the effectiveness of aerobic exercise on improving sleep in patients with systemic lupus erythematosus. The subjects will do treadmill 2 times per week, from 15-20 min. with low to moderate(55-65% maxCF) intensity exercise, so 30 min. until 4ª week. From the 5ª to 8ª week they will be able to make greater efforts to 35-40 min. totalizing 16 weeks. The control group will not do exercise and will receive education class about disease, health, sleep, 1 time per month.

Conditions

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Systemic Lupus Erythematosus Sleep Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Aerobic Exercise

Subjects will follow one defined exercise process, according their cardiopulmonary exercise test, during 16 weeks, two times per a week.

Group Type EXPERIMENTAL

Aerobic Exercise

Intervention Type PROCEDURE

From 1st week up to and including 4th week, subjects will do: 5 minutes warm-up, then 15-30 minutes low to moderate (55-65% VO2) exercise, then 15 minutes stretching. From 5th week up to and including 16th week, subjects will do: 5 minutes warm-up, then intermittent training for between 30-40 minutes, then 10 minutes stretching.

Control Group

A non-exercise group will receive regular educational information relating to their condition.

Group Type EXPERIMENTAL

Control Group

Intervention Type OTHER

The control group will have monthly meetings to learn about: good sleep habits, Systemic Lupus Erythematosus (their disease) and general good health.

Interventions

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Aerobic Exercise

From 1st week up to and including 4th week, subjects will do: 5 minutes warm-up, then 15-30 minutes low to moderate (55-65% VO2) exercise, then 15 minutes stretching. From 5th week up to and including 16th week, subjects will do: 5 minutes warm-up, then intermittent training for between 30-40 minutes, then 10 minutes stretching.

Intervention Type PROCEDURE

Control Group

The control group will have monthly meetings to learn about: good sleep habits, Systemic Lupus Erythematosus (their disease) and general good health.

Intervention Type OTHER

Other Intervention Names

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Physical activity Physical training

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of Systemic Lupus Erythematosus (SLE) according American College of Rheumatology (ACR) Criteria revised in 1997;
* Pittsburgh sleep quality index (PSQI) ≥ 5;
* Free and Clarified Consent Term signature.

Exclusion Criteria

* Patients who have other rheumatologic diseases (rheumatoid arthritis, sjogren syndrome, fibromyalgia, ankylosis spondylitis), excerpt mild osteoarthritis;
* Systemic Lupus Erythematosus Disease Assessment Index (SLEDAI) \> 8;
* Untreated diseases: Hypertension, diabetes mellitus (DM), dyslipidemia, thyroid dysfunction, cardiorespiratory diseases, malignancies;
* Patients who do not accept the study rules as time and/or follow-up exercise program time proposed;
* Suspected or pregnancy confirmation;

\* Patients who are taking sleeping medication;
* Patients who won´t sign the Free and Clarified Consent Term informed;
* Patients engaged in physical activity (defined as previously sedentary individuals, or that which do not perform any type of regular physical activity at least six months);
Minimum Eligible Age

18 Years

Maximum Eligible Age

69 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Federal University of São Paulo

OTHER

Sponsor Role lead

Responsible Party

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Lilian K C Reis, Principal Investigator

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Lilian KC Reis

Role: STUDY_CHAIR

Federal University of São Paulo UNIFESP

Virginia FM Trevisani

Role: PRINCIPAL_INVESTIGATOR

Federal University of São Paulo

Locations

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Psychobiology and Exercise Studies Centre

São Paulo, São Paulo, Brazil

Site Status RECRUITING

Countries

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Brazil

Central Contacts

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LILIAN REIS

Role: CONTACT

+55 1193869111

Facility Contacts

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Lílian Reis

Role: primary

+55 11 993869111

Other Identifiers

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03315312.8.0000.5505

Identifier Type: -

Identifier Source: org_study_id

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