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Combined and Isolated Effects of Sleep Deprivation and Alcohol Intake on Exercise Performance in Humans.

NCT ID: NCT02117193

Last Updated: 2016-12-21

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-10-31

Study Completion Date

2015-05-31

Brief Summary

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Although the effects of acute alcohol intake and sleep deprivation on exercise performance lacks evidence in the literature, in many situations, they occur simultaneously. Once the alcohol affects physiological processes, the processes that occur during sleep can be impaired, such as: suppression of GH release, action of neurotransmitters and neuromodulators in the CNS, changes in the proportion of sleep stages and may lead to suppression of REM sleep. These changes promote a significant functional impairment such as a reduction in alertness and modification in reaction time, which affects the performance of any activity of daily and professional life. However, the combined effects on the physical performance variables, such as aerobic and neuromuscular performance lack of evidence in the literature.

Detailed Description

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Ten subjects were randomized in four situations after familiarization and control situation: (1) alcohol intake combined with sleep normal; (2) alcohol intake combined with sleep deprivation; (3) placebo intake combined with sleep normal and (4) placebo intake combined with sleep deprivation.

Conditions

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Alcohol Intake Sleep Deprivation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Alcohol intake

1 g/kg of etanol combined. Beer without alcohol in the same volume will be used to placebo condition.

Group Type PLACEBO_COMPARATOR

Alcohol intake

Intervention Type OTHER

The subjects will be drink beer (with or without alcohol) before sleep intervention (normal sleep and sleep deprivation).

Sleep deprivation

Intervention Type OTHER

One night of sleep deprivation or one night of normal sleep.

sleep deprivation

one night of sleep deprivation will be compared to 8h of normal sleep.

Group Type ACTIVE_COMPARATOR

Alcohol intake

Intervention Type OTHER

The subjects will be drink beer (with or without alcohol) before sleep intervention (normal sleep and sleep deprivation).

Sleep deprivation

Intervention Type OTHER

One night of sleep deprivation or one night of normal sleep.

Interventions

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Alcohol intake

The subjects will be drink beer (with or without alcohol) before sleep intervention (normal sleep and sleep deprivation).

Intervention Type OTHER

Sleep deprivation

One night of sleep deprivation or one night of normal sleep.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

\- Physical active men

Exclusion Criteria

* AUDIT questionnaire above 15 points
* Nocturnal Chronotype
* Skeletal muscle injuries in upper and lower limb
* Metabolic and cardiovascular disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, Brazil

OTHER

Sponsor Role collaborator

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.

OTHER_GOV

Sponsor Role collaborator

Federal University of Rio Grande do Sul

OTHER

Sponsor Role lead

Responsible Party

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Marco Aurélio Vaz, PhD

PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Rodrigo Rodrigues, MSc

Role: PRINCIPAL_INVESTIGATOR

Federal University of Rio Grande do Sul

Locations

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Exercise Research Laboratory

Porto Alegre, Rio Grande do Sul, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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UFRGS 366465

Identifier Type: -

Identifier Source: org_study_id