Aerobic Exercise: A Potential Rescue From the Negative Ramifications of Poor Sleep

NCT ID: NCT06956963

Last Updated: 2025-07-30

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-07-21
• Study Completion Date: 2026-01-31

Brief Summary

The goal of this interventional study is to differentiate the effects of an acute partial sleep deprivation intervention on markers of cardiovascular health, cardio-autonomic function, physical and cognitive performance, as well as overall wellbeing in active vs sedentary individuals. The main aims of the project are:

• To differentiate the effects of partial sleep deprivation on central hemodynamics (i.e., central blood pressure and arterial stiffness) in active vs sedentary individuals.
• To differentiate the effects of partial sleep deprivation on physical (i.e., handgrip strength and reactive strength index) and cognitive performance (i.e., reaction time and impulse control) in active vs sedentary individuals.
• To differentiate the effects of partial sleep deprivation on overall wellbeing (i.e., cardio-autonomic function, inflammation levels, and psychological mood states) in active vs sedentary individuals.

Participants will be divided into two groups based on aerobic activity level - active or sedentary - and assessed for markers of cardiovascular health, cardio-autonomic function, physical and cognitive performance, as well as overall wellbeing before and after three days of normal sleep and three days of partially deprived sleep (i.e., 30% reduction in total time in bed).

Conditions

Cardiovascular Health; Sleep

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: OTHER
• Blinding Strategy: NONE

Study Groups

Normal Sleep

Group Type: NO_INTERVENTION

No interventions assigned to this group

Acute Partial Sleep Deprivation

30% reduction in habitual time in bed

Group Type: EXPERIMENTAL

Partial Sleep Deprivation

Intervention Type: OTHER

30% reduction in habitual time in bed

Interventions

Partial Sleep Deprivation

30% reduction in habitual time in bed

Intervention Type: OTHER

Other Intervention Names

Reduced Sleep

Eligibility Criteria

Inclusion Criteria

• Chronically active (≥150 minutes of moderate- and/or ≥75 minutes of vigorous-intensity aerobic exercise per week for the last 3 months) OR
• Sedentary (≤60 minutes of aerobic exercise per week for the last 3 months)

Exclusion Criteria

• Chronic, uncontrolled disease (cardiovascular, metabolic)
• Poor sleep (regularly achieving <7 hours of sleep per night)
• Musculoskeletal injury in the last 6 months
• Obese (grade II or higher)
• Pregnant

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 39 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Florida State University

OTHER

Sponsor Role: lead

Responsible Party

Michael J. Ormsbee

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Institute of Sports Sciences and Medicine

Tallahassee, Florida, United States

Site Status: RECRUITING

Countries

United States

Central Contacts

Brett Cross

Role: CONTACT

bcross2@fsu.edu

4783089421

Michael Ormsbee

Role: CONTACT

mormsbee@fsu.edu

Facility Contacts

Michael Ormsbee

Role: primary

mormsbee@fsu.edu

6103313126

Other Identifiers

STUDY00006067

Identifier Type: -

Identifier Source: org_study_id