Neuromuscular and Cognitive Fatigue During a 24 Hour Treadmill Running Exercise

NCT ID: NCT00428779

Last Updated: 2009-06-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-09-30

Study Completion Date

2007-12-31

Brief Summary

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The main purpose of the present study is to determine the relative contributions of central and peripheral fatigue during an ultra-endurance exercise.

Detailed Description

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For that purpose, 14 subjects running 24 hours on a treadmill will be compared with a control group being awake during the same period. Subjects who running will have electrically evoked forces on the muscles associated EMG activity, blood samples and muscle biopsy.

Conditions

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Healthy

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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1

patients running during 24 hours without sleep

Group Type EXPERIMENTAL

running during 24 hours without sleep

Intervention Type PROCEDURE

patients running during 24 hours without sleep

2

patients without sleep during 24 hours

Group Type PLACEBO_COMPARATOR

no sleeping

Intervention Type OTHER

patients without sleep during 24 hours

Interventions

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running during 24 hours without sleep

patients running during 24 hours without sleep

Intervention Type PROCEDURE

no sleeping

patients without sleep during 24 hours

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* The subjects of the experimental group will be recruited among experienced ultra-runners . They all have run at least a 12 hour race or longer.
* The control group will be recruited among experienced ultra-runners . Age of control group will be age experimental group more or less 2 years.

Exclusion Criteria

* The subjects will not be selected if:

* they were injured in the 3 months before the experiment
* they had a tendon or joint pathology that could impair strength measurements.
* they participate to an other experiment at the same time
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Centre Hospitalier Universitaire de Saint Etienne

OTHER

Sponsor Role lead

Responsible Party

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CHU de Saint-Etienne

Principal Investigators

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DENIS Christian, Professor

Role: STUDY_CHAIR

Service de médecine du sport, CHU SAINT-ETIENNE

Locations

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Pr André GEYSSANT

Saint-Etienne, , France

Site Status

Countries

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France

References

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Morin JB, Samozino P, Feasson L, Geyssant A, Millet G. Effects of muscular biopsy on the mechanics of running. Eur J Appl Physiol. 2009 Jan;105(2):185-90. doi: 10.1007/s00421-008-0888-2. Epub 2008 Oct 8.

Reference Type RESULT
PMID: 18841378 (View on PubMed)

Jamart C, Francaux M, Millet GY, Deldicque L, Frere D, Feasson L. Modulation of autophagy and ubiquitin-proteasome pathways during ultra-endurance running. J Appl Physiol (1985). 2012 May;112(9):1529-37. doi: 10.1152/japplphysiol.00952.2011. Epub 2012 Feb 16.

Reference Type DERIVED
PMID: 22345427 (View on PubMed)

Other Identifiers

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DGS 2006-0111

Identifier Type: -

Identifier Source: secondary_id

2006-A00312-49

Identifier Type: -

Identifier Source: secondary_id

0601095

Identifier Type: -

Identifier Source: org_study_id

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