Combined Effects of Acute Sleep Restriction and Moderate Acceleration (+Gz) on Physiological and Behavioral Responses to High Mental Workload

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

28 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-09-11

Study Completion Date

2025-11-30

Brief Summary

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Fighter pilots have to perform tasks requiring high mental workload during moderate-intensity acceleration phases (2 to 3G) that can last several minutes. When these accelerations are performed in the body axis (+Gz), they induce a redistribution of blood flow in the lower limbs associated with a decrease in cerebral blood flow, partially compensated by activation of the sympathetic nervous system (baroreflex).

The main hypothesis is that the effects of these prolonged accelerations, even of moderate intensity (\<+4Gz), could impair pilots' ability to perform complex cognitive tasks, with potential consequences for flight safety and mission conduct.

Moreover, flight missions are often performed after sleep debt, which is known to induce cardiovascular responses, sympathetic nervous system activation and impaired mental performance.

The secondary hypothesis is that sleep debt (3h of time spent in bed) may increase the impairment of cognitive performance during prolonged acceleration.

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Detailed Description

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Conditions

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Sleep Deprivation

Study Design

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Observational Model Type

CASE_CROSSOVER

Study Time Perspective

PROSPECTIVE

Study Groups

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Group A : Usual sleep 2 ; Deprivation 2

V1-\>V3 id. V4 : Usual sleep and test series (easy; difficult; difficult) V5 : Usual sleep and test series (difficult; easy; easy) V6 : Sleep deprivation and test series (easy; easy; difficult) V7 : Sleep deprivation and test series (difficult; difficult; easy)

Partial sleep deprivation

Intervention Type OTHER

Group B : Usual sleep ; Deprivation; Deprivation ; Usual sleep

V1-\>V3 id. V4 : Usual sleep and test series ( difficult; difficult ; easy) V5 : Sleep deprivation and test series (easy; difficult; difficult) V6 : Sleep deprivation and test series (difficult; easy; easy) V7 : Usual sleep and test series (easy ; easy ; difficult)

Partial sleep deprivation

Intervention Type OTHER

Group C : Deprivation; Usual sleep ; Deprivation ; Usual sleep

V1-\>V3 id. V4 : Sleep deprivation and test series (easy; easy; difficult) V5 : Usual sleep and test series (difficult; difficult; easy) V6 : Sleep deprivation and test series (easy; difficult; difficult) V7 : Usual and test series (difficult; easy; easy)

Partial sleep deprivation

Intervention Type OTHER

Group D : Deprivation ; Deprivation ; Usual sleep ; Usual sleep

V1-\>V3 id. V4 : Sleep deprivation and test series (difficult; easy; easy) V5 : Sleep deprivation and test series (easy; difficult; easy) V6 : Usual sleep and test series ( difficult; easy ; easy) V7 : Usual sleep and test series (easy ; difficult; difficult)

Partial sleep deprivation

Intervention Type OTHER

Interventions

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Partial sleep deprivation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy subject (male or female);
* Tobacco consumption \< 5 cigarettes per day or nicotine-free vapour;
* Regular physical activity (between 1 and 8 hours per week);
* Affiliated or entitled to a social security scheme;
* Having given their consent.

Exclusion Criteria

* Presenting an active medical pathology or a history \<6 months (cardiological, renal, hepatic, cutaneous, neurological, psychiatric...), or a significant deviation from normal values observed during questioning, clinical examination or electrocardiogram (ECG);
* BMI \> 30 (cardiovascular risk factor);
* Have a medical contraindication to sporting activities;
* Taking a medical treatment;
* Habitual sleep duration \< 6 hours;
* Presenting a sleep disorder confirmed by questionnaire (Pittsburgh Sleep Quality Index Questionnaire \> 5);
* Pregnant or breastfeeding
* Not covered by a health insurance plan;

Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes