Frequency of Diagnostic Symptomatic Pulmonary Embolism's in Patients Hospitalized for Clinical Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)

NCT ID: NCT02035293

Last Updated: 2017-12-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

750 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-01-08

Study Completion Date

2017-10-13

Brief Summary

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A standardized diagnostic strategy of pulmonary embolism will be applied to eligible patients, incorporating a clinical probability score (revised Geneva score), plasma D-dimer assay and if necessary, a multidetector-row CT angiography thoracic and venous ultrasound of the lower limbs. All the patient with a pulmonary embolism diagnosed or not, will be followed for 3 months.

Detailed Description

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Conditions

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Chronic Obstructive Pulmonary Disease Patients Hospitalized for a COPD Exacerbation

Keywords

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COPD Exacerbation Pulmonary embolism Standardized and consensus diagnostic strategy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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PEP

No drug and no placebo were used in this study. For all the patients who participated at the study PEP, only following exams must be performed: a clinical probability score (revised Geneva score), plasma D-dimer assay and if necessary, a chest multidetector-row CT angiography and venous ultrasound of the lower limbs

Group Type OTHER

PEP

Intervention Type OTHER

Interventions

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PEP

Intervention Type OTHER

Other Intervention Names

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No drug and no placebo were used in this study. For all the patients who participated at the study PEP, only exams must be performed;

Eligibility Criteria

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Inclusion Criteria

* Patients hospitalized for a COPD exacerbation
* COPD previously diagnosed

Exclusion Criteria

* Allergy to iodinated contrast
* Creatinine clearance \< 30 mL / min
* Patient hospitalized for exacerbation of COPD for more than 48 hours
* Pneumothorax
* Exams impossible to be performed
* Pregnancy
* Life expectancy \< 3 months
* Patients already receiving anticoagulant therapy for another reason (mechanical valve, cardiac arrhythmia).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Brest

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Francis COUTURAUD, PU-PH

Role: PRINCIPAL_INVESTIGATOR

CHRU de Brest

Locations

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CHU

Angers, , France

Site Status

CHRU de Brest

Brest, , France

Site Status

HIA

Brest, , France

Site Status

CHU Clermont-Ferrand

Clermont-Ferrand, , France

Site Status

Hôpital Européen Georges Pompidou

Paris, , France

Site Status

CH de Cornouaille Quimper

Quimper, , France

Site Status

Hôpital Nord

Saint-Etienne, , France

Site Status

Countries

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France

Other Identifiers

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RB 13-087 [CHRU Brest]

Identifier Type: -

Identifier Source: secondary_id

PEP

Identifier Type: -

Identifier Source: org_study_id