The Stockholm Sleepy Brain Study: Effects of Sleep Deprivation on Cognitive and Emotional Processing in Young and Old

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

98 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-11-30

Study Completion Date

2014-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The main purpose of this study is to investigate the effects of partial sleep deprivation (PSD) on resting state brain connectivity, emotional contagion, empathy, and emotional regulation.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Neurobehavioral Effects of Partial Sleep Deprivation

NCT02128737

Control 1 Night Recovery Sleep 3 Nights Recovery Sleep +1 more

COMPLETED NA

Metabolic and Cognitive Parameters Following Partial Sleep Deprivation

NCT01823263

Sleep Deprivation Sleep

UNKNOWN NA

The Effect of Sleep Loss on Emotion Regulation

NCT05393830

Sleep Insomnia Sleep Deprivation

RECRUITING NA

Neural Mechanisms Underlying the Antidepressant Effects of Sleep Deprivation

NCT03169543

Depression, Unipolar

COMPLETED NA

Cardiovascular Effects of Partial Sleep Deprivation

NCT00669513

Sleep Deprivation

COMPLETED PHASE3

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Sleep Deprivation

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Sleep deprivation

Partial sleep deprivation allowing 3 h sleep at night

Group Type EXPERIMENTAL

Partial sleep deprivation allowing 3 h sleep at night

Intervention Type BEHAVIORAL

Participants sleep at home while monitored with ambulatory polysomnography. For the full sleep condition, they are instructed to go to bed and to get up at the usual times that they would normally do that. For the sleep deprivation condition, they are instructed to go to bed 3 hours before the time when they would usually get up, and then to get up at that time.

Full sleep

Sleep with no restriction

Group Type EXPERIMENTAL

Full sleep

Intervention Type BEHAVIORAL

Participants sleep at home while monitored with ambulatory polysomnography. For the full sleep condition, they are instructed to go to bed and to get up at the usual times that they would normally do that. For the sleep deprivation condition, they are instructed to go to bed 3 hours before the time when they would usually get up, and then to get up at that time.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Partial sleep deprivation allowing 3 h sleep at night

Participants sleep at home while monitored with ambulatory polysomnography. For the full sleep condition, they are instructed to go to bed and to get up at the usual times that they would normally do that. For the sleep deprivation condition, they are instructed to go to bed 3 hours before the time when they would usually get up, and then to get up at that time.

Intervention Type BEHAVIORAL

Full sleep

Participants sleep at home while monitored with ambulatory polysomnography. For the full sleep condition, they are instructed to go to bed and to get up at the usual times that they would normally do that. For the sleep deprivation condition, they are instructed to go to bed 3 hours before the time when they would usually get up, and then to get up at that time.

Intervention Type BEHAVIORAL

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Sleep restriction Sleep loss

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 20-30 years of age, inclusive OR 65-75 years of age, inclusive
* Able to understand spoken and written Swedish (in order to understand instructions)
* Normal or corrected-to-normal vision not using glasses
* Not colour blind
* Right-handed
* Free from ferromagnetic objects in body
* No history of any neurologic or psychiatric illness including drug abuse
* No history of diabetes nor hypertension

* No depression according to ratings using the Hospital Anxiety and Depression scale (HAD)
* No insomnia according to ratings using the Insomnia Severity Index (ISI) and Karolinska Sleep Questionnaire (KSQ)
* No use of psychotropic drugs
* Not studying or working in medicine, psychology, nor behavioural science
* Not suffering from severe seasonal allergy
* No use of cortisone, anti-histamines, nor any other immune-modulating drugs
* Habitual intake of no more than 4 cups of coffee per day or the equivalent in terms of caffeine
* No daily use of nicotine