Effect of Partial Sleep Deprivation on Cognition and Cytokines in Individuals With Major Depression

NCT ID: NCT00291239

Last Updated: 2009-04-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-02-28

Study Completion Date

2009-07-31

Brief Summary

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40 patients with the diagnosis of major depression are included. There are two interventions: partial sleep deprivation (PSD) and normal night sleep (CTRL). Patients are randomly assigned to PSD-(2 undisturbed nights)-CTRL or CTRL-(2 undisturbed nights)-PSD. Cytokine-status, neuropsychological and psychopathometric status are assessed pre and post each interventional and control condition.

Detailed Description

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Conditions

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Major Depression

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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partial sleep deprivation

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Major depression
* Informed consent

Exclusion Criteria

* Known epilepsy or previous unexplained loss of consciousness after sleep deprivation
* Bipolar disorder
* Acute or chronic inflammatory diseases
* Psychosis
* Suicidal tendency
* Pregnancy or nursing
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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German Research Foundation

OTHER

Sponsor Role collaborator

Zentrum für Integrative Psychiatrie

OTHER

Sponsor Role lead

Principal Investigators

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Dunja Hinze-Selch, MD

Role: PRINCIPAL_INVESTIGATOR

Zentrum für Integrative Psychiatrie

Locations

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Zentrum für Integrative Psychiatrie

Kiel, , Germany

Site Status

Countries

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Germany

Other Identifiers

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DFG-SFB 654, C5 "IL-6-MDE"

Identifier Type: -

Identifier Source: secondary_id

WADE

Identifier Type: -

Identifier Source: org_study_id

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