Evaluation of the Links Between Sleep Disorders and the Risk of Suicide Attempt

NCT ID: NCT03793699

Last Updated: 2020-09-11

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 60 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2019-02-04
• Study Completion Date: 2022-12-31

Brief Summary

Several studies have demonstrated an association between sleep disorders such as insomnia and nightmares to suicidal ideations and behaviors.

Nevertheless, some of these studies are methodologically questionable especially in the exploration of sleep disorders. Furthermore, confounding factors such as depressive symptomatology are not controlled and the measurement of suicidal behavior has often been taken into account as a historical measure, not as a current event, which introduces uncertainties and a lack of precision regarding the temporality of the phenomena.

Today, while the links between sleep disorders and suicidal risk are well known, we have a lack of information on the importance and the role of sleep disorders as a precipitating factor. Indeed, few studies have evaluated the temporal link between sleep disorders and suicidal acts.

The objective of this study is to evaluate the links between acute and chronic sleep disorders and the risk of suicide attempt

Detailed Description

Pilot, prospective, monocentric case-control study.

There are 2 groups of subjects :

• group of patients who have made a suicide attempt
• control group with only suicidal ideas

First visit V1 is performed within the first 72 hours of hospitalization. A re-assessment is scheduled 1 month after (V2).

At V1, collected parameters are : chronic sleep disorders, chronotype, specific sleep disorders in posttraumatic stress disorder, nightmares and the distress associated, childhood trauma, cognitive dysfunction, suicidal ideation and psychopathologic assessment.

At V2, we assess evolution of sleep disturbances and suicidal ideation.

Conditions

Attempted Suicide

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: PROSPECTIVE

Study Groups

case group : realized a suicide attempt

adults having realized a suicide attempt and without histories of suicide attempt.

No interventions assigned to this group

control group : only suicidal ideas

adults having suicidal ideas without suicidal acting out and without histories of suicide attempt.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

Criterion specific to the studying group :

• Subjects hospitalized and whose indication of hospitalization is a suicide attempt by voluntary drug intoxication or phlebotomy during the last 72 hours, without any history of attempted suicide

Criterion specific to the control group:

• Subjects hospitalized since less than 72 hours, and whose indication of hospitalization is the presence of suicidal ideas, without any history of attempted suicide

Exclusion Criteria

• Pregnant of lactating women
• Diagnosed dementia pathology
• Proven intellectual disability
• Patient whose physical or mental state does not allow the passing of the tests of the study
• Under protective measures (guardianship/supervision)
• Refusal to participate in the study
• Diagnosed with chronic or severe psychiatric illness (psychotic disorder, bipolarity)

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Hospital, Lille

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Vincent JARDON, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Lille

Locations

Hôpital Fontan, CHU

Lille, , France

Site Status: RECRUITING

Countries

France

Central Contacts

Vincent JARDON, MD

Role: CONTACT

vincent.jardon@chru-lille.fr

320 44 45 84 ext. +33

Other Identifiers

2017-A03649-44

Identifier Type: OTHER

Identifier Source: secondary_id

2017_55

Identifier Type: -

Identifier Source: org_study_id