The Effects of Administration of Combined Docosahexaenoic Acid and Vitamin E Supplements on Spermatogram and Seminal Plasma Oxidative Stress in Infertile Men With Asthenozoospermia
NCT ID: NCT01846325
Last Updated: 2015-06-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2/PHASE3
180 participants
INTERVENTIONAL
2013-12-31
2015-05-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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DHA plus vitamin E
Cap DHA 460mg plus vitamin E 600mg per day
vitamin E
DHA
VitaminE plus placebo
vitamin E 600 mg plus placebo
vitamin E
placebo
placebo plus placebo
DHA shaped placebo plus vitamin E shaped placebo
placebo
DHA plus placebo
460 mg DHA plus placebo
DHA
placebo
Interventions
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vitamin E
DHA
placebo
Eligibility Criteria
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Inclusion Criteria
* should be infertile (no conception after 12 months intercourse without any contraception)
* age 20-45 y.o, idiopathic asthenospermia according to WHO criteria
* normal hormonal profile
Exclusion Criteria
* any anatomical abnormality in GU tract
* any chronic disease during last 3 months
* any surgery in GU tract
* consumption of omega-3 fatty acids and/or vitamin E supplements during last 3 months
20 Years
45 Years
MALE
No
Sponsors
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National Nutrition and Food Technology Institute
OTHER
Responsible Party
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Dr Azita Hekmatdoost
Dr
References
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Eslamian G, Amirjannati N, Noori N, Sadeghi MR, Hekmatdoost A. Effects of coadministration of DHA and vitamin E on spermatogram, seminal oxidative stress, and sperm phospholipids in asthenozoospermic men: a randomized controlled trial. Am J Clin Nutr. 2020 Sep 1;112(3):707-719. doi: 10.1093/ajcn/nqaa124.
Other Identifiers
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046401
Identifier Type: -
Identifier Source: org_study_id
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