Impact of Transcranial Direct Current Stimulation of the Motor Cortex on Language Functions in Residual Aphasia
NCT ID: NCT01845129
Last Updated: 2013-05-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
16 participants
INTERVENTIONAL
2013-04-30
2014-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
TRIPLE
Study Groups
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anodal tDCS
atDCS will be administered for 20 minutes with 1 milliampere (1 mA) to the left primary hand motor cortex
atDCS
atDCS will be delivered with a constant current of 1 mA during simultaneous resting-state (RS) and task-related (picture naming) functional magnetic resonance imaging (fMRI). The current will be turned on prior to the RS-fMRI scan and continues for 20 minutes.
sham tDCS
During sham the current will be increeased and decreased in a ramp-like fashion (10 sec)
sham tDCS
sham tDCS will be administered to the left primary hand motor cortex
atDCS
atDCS will be delivered with a constant current of 1 mA during simultaneous resting-state (RS) and task-related (picture naming) functional magnetic resonance imaging (fMRI). The current will be turned on prior to the RS-fMRI scan and continues for 20 minutes.
sham tDCS
During sham the current will be increeased and decreased in a ramp-like fashion (10 sec)
Interventions
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atDCS
atDCS will be delivered with a constant current of 1 mA during simultaneous resting-state (RS) and task-related (picture naming) functional magnetic resonance imaging (fMRI). The current will be turned on prior to the RS-fMRI scan and continues for 20 minutes.
sham tDCS
During sham the current will be increeased and decreased in a ramp-like fashion (10 sec)
Eligibility Criteria
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Inclusion Criteria
* German native speaker
* cerebrovascular stroke in left hemisphere (\>6 months)
* mild aphasia (according to Aachen Aphasia Test Battery Classification, Huber et al., 1983)
* residual anomia in naming test (\>75 correct responses)
Exclusion Criteria
* alcohol or drug abuse
* MRI contraindication (e.g. magnetic metal, pacemaker, claustrophobia)
18 Years
80 Years
ALL
No
Sponsors
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Charite University, Berlin, Germany
OTHER
Responsible Party
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Marcus Meinzer
Creutzfeldt Fellow
Principal Investigators
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Marcus Meinzer, PhD
Role: PRINCIPAL_INVESTIGATOR
Charite, University Medicine, Neurology
Agnes Flöel, MD
Role: PRINCIPAL_INVESTIGATOR
Charite, University Medicine, Neurology
Locations
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Charite, University Medicine, Dept. of Neurology
Berlin, State of Berlin, Germany
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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RAPH_01EO0801
Identifier Type: -
Identifier Source: org_study_id
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